PURPOSE Fornix contracture is an obstacle for fitting a prosthesis in blind or enucleated patients, and may lead to disfigurement and psychological issues. This study evaluates the efficacy of amniotic membrane transplantation (AMT) for fornix reconstruction with the aim of better retention of the ocular prosthesis. METHODS This non-comparative interventional case series includes eighteen bli...

The mole (Talpa europaea; Insectivora) and the mole rat (Spalax ehrenbergi; Rodentia) both have degenerated eyes as a convergent adaptation to subterranean life. The rudimentary eye lenses of these blind mammals no longer function in a visual process. The crystallin genes, which display a lens-specific expression pattern, were studied in these blind mammals and in related species with normal ey...

Background: Glaucoma in children presents difficult clinical challenges. Even when appropriately tr blindness can occur. Design: Retrospective interventional case series and literature review. Methods: All c records of children seen by the author with a diagnosis of glaucoma established before 16 years of age were rev from 1977 to 2003. Glaucoma was classified as primary infantile, aphakic, syn...

A series of 23 eyes removed after cobalt plaque therapy for malignant melanoma of the choroid is presented, and the histological changes are described with particular reference to the presence or absence of necrosis in the tumours. In 17 of the 23 eyes no evidence of tumour necrosis was found, though all showed evidence of radiation changes in the adjacent tissues. Necrosis was found in 6 cases...

Results: Among 313 eligible subjects, 242 (77%) could be contacted, of whom 176 (73%) were examined. Of those who were examined, mean±SD age was 69.3±10.5 years, 66.5% were female, 35 had been operated on bilaterally at Sanrao, and 85.2% had a preoperative presenting visual acuity of 6/60 or worse. Presenting and best-corrected postoperative acuity in the eye that was operated on were 6/18 or b...

AIMS A prospective, randomised, double blind, placebo controlled study of intraoperative mitomycin C as adjunctive treatment of primary pterygium was conducted. METHODS A total of 66 eyes of 54 patients with primary pterygium were treated with excision, with or without a single intraoperative application of mitomycin C (0.1 mg/ml for 5 minutes) to evaluate the efficacy and toxicity of this ad...

The oldest preserved visual systems are to be found in the extinct trilobites, marine euarthropods which existed between about 520 and 250 million years ago. Because they possessed a calcified cuticle, they have a good fossil record, and commonly the lens-bearing surfaces of their paired compound eyes are well preserved. The sublensar structures, however, remain unknown. Three kinds of eyes hav...