Intrinsic Consequence of LigandMimetic Properties To the Editor: An intrinsic activating property of GPIIb/IIIa blockers as first described by us in 19981 is widely discussed as one potential contributing factor for the disappointing outcome of trials with oral GPIIb/IIIa blockers. In a recent article in Circulation, Frelinger et al2 question the existence of an activating property of GPIIb/III...

OBJECTIVE To investigate the risk factors of symptomatic bradyarrhythmias in relation to β-blockers use. METHODS A hospital-based case-control study [228 patients: 108 with symptomatic bradyarrhythmias (cases) and 120 controls] was conducted in Sultanah Aminah Hospital, Malaysia between January 2011 and January 2014. RESULTS The mean age was 61.1 ± 13.3 years with a majority of men (68.9%)....

INTRODUCTION According to the convincing evidence, a decline in mortality rate has been achieved with beta-blockers in patients with an acute myocardial infarction and in post-infarction follow-up. In fact, there has been a clear reduction of sudden coronary death. The necessary condition for the efficiency of beta-blockers is an early use. They are also a medication of choice for angina after ...

Objective: The study was conducted to identify the prescribing practices in essential hypertension to find out prescribing patterns in elderly patients. Material and methods: A retrospective study was done to assess the pattern and prescription of antihypertensive drugs at Maharishi Markandeshwar Medical College and Hospital, Kumarhatti Solan (H.P) A total of 100 handwritten prescriptions of pa...