a case of tropical eosinophylia which seems to be an independent disease is described. the patient was admitted because of fever, loss of weight- ~and some respiratory disorders. the blood examination shows a high percentage of eosinophylia in several times. in this view other causes of the blood eosinophylia were eliminated by the laboratory tests. the patient was treated with arsenical drugs ...

stem cells are undifferentiated self regenerating multi potential cells. there are three types of stem cells categories by the ability to form after cells and correlated with the body’s development process. totipotent: these stem cells can form an entire organism such as fertilized egg. ploripotent: ploripotent cells are those that can form any cell in the body but cannot form an entire organis...

Most human cells have no direct contact with the external environment and their living conditions are ensured by blood. An essential criterion for normal blood circulation is the ability of the blood to arrest bleeding at sites of tissue injury and to prevent thrombus formation inside the blood vessels under normal conditions. The balance between these two extreme states is rigorously controlle...

The concept of introducing genes into human cells for therapeutic purposes developed nearly 50 years ago as diseases due to defects in specific genes were recognized. Development of recombinant DNA techniques in the 1970s and their application to the study of mouse tumor viruses facilitated the assembly of the first gene transfer vectors. Vectors of several different types have now been develop...

Microvascular circulation plays a vital role in regulating physiological functions, such as vascular resistance, and maintaining organ health. Pathologies such as hypertension, diabetes, or hematologic diseases affect the microcirculation posing a significant risk to human health. The retinal vasculature provides a unique window for non-invasive visualisation of the human circulation in vivo an...

155 PEDIATRICS, January 1958 DR. SCHULMAN: The case we would like to discuss is one chosen for its own intrinsic interest, and also because it provides a good opportunity to illustrate some of our newer know!edge of coagulation in general, and hemophilia in particular. The patient is a 4-year-old boy who was referred to this hospital for investigation of a hemorrhagic diathesis. His birth was n...

Disorders of white cells are very common in clinical practice. White-cell development and numbers are controlled by a mixture of external stimuli including cytokines, matrix proteins, and accessory cells. Several different white-cell lineages are recognised; each has a role in host defence. Both white-cell deficiency and overproduction can lead to disease. Some forms of inherited white-cell def...

Acid-base physiology is among the most complex topics in clinical medicine. Disturbances of this system are common in the critically ill, and important clinical decisions based on measured acid-base parameters occur on a daily, even hourly basis. Therefore, a sound understanding of acid-base physiology is mandatory for the intensivist. The field is full of complicated concepts and equations tha...

Anemia is an absolute decrease in the number of circulating red blood cells (RBCs). The diagnosis is made when laboratory measurements fall below accepted normal values (Table 121-1). In emergency medicine, anemia is divided into two broad categories: emergent, having immediate life-threatening complications; and nonemergent, with less imminent danger to the patient. Factors other than the abso...