A direct method is described, in which a single reagent is used without deproteinization, for measuring blood urea nitrogen (BUN) in serum. The reagent is a mixture of diacetylmonoxime, antipyrine (phenazone), and arsenic pentoxide in acid solution. Lipemia, bilirubin to 25 mg/100 ml, hemoglobin to 1g/100 ml, and protein to 20g/100 ml do not affect the results. Beer’s law is followed at 460 nm ...

The diagnosis of acute kidney injury (AKI) is usually based on measurements of blood urea nitrogen (BUN) and serum creatinine. BUN and serum creatinine are not very sensitive or specific for the diagnosis of AKI because they are affected by many renal and nonrenal factors that are independent of kidney injury or kidney function. Biomarkers of AKI that are made predominantly by the injured kidne...

This experiment was conducted to investigate the effect of a Bacillus spp.–based directfed microbial (DFM) on growth performance, apparent total tract digestibility (ATTD), blood profile, intestinal histomorphology, and fecal gas emission in piglets fed corn and soybean meal–based diets. The DFM product was based on 1 strain of Bacillus subtilis and 2 strains of Bacillus amyloliquefaciens and f...

The protective effect of methanolic extract of milk thistle seeds and silymarin against cisplatin-induced renal toxicity in male rats after a single intraperitoneal injection of 3 mg kg cisplatin were studied. Over 5 days, cisplatin-treated rats showed tubular necrosis and elevation in blood urea nitrogen (BUN) and serum creatinine (Scr). Pretreatment of animals with silymarin (50 mg kg) or ext...

results bw was lower for the 5/6 nx group rats after the operations compared with the bw of those in the sham operation group. furthermore, the 5/6 nx group showed elevations in blood pressure, cr, bun, alt, and ast levels compared with the sham group over the course of time. conclusions in summary, ckd induced by the 5/6 nx model caused hypertension and increased serum levels of cr, bun, alt, ...

OBJECTIVE This study defines the relationship between salivary beta-2 microglobulin (β2-M) and intensity of uremia in male patients diagnosed with chronic renal failure (CRF). MATERIALS AND METHODS In total of 42 males were enrolled in a case-control study. There were 21 cases of CRF and 21 control cases. We collected 10cc of saliva plus 5 cc of blood from all patients to determine β2-M, bloo...

Crossed fused renal ectopia is a rare congenital malformation. We describe a case in which a 58-year-old male with left-sided crossed fused renal ectopia presented with urinary bladder outlet obstruction due to metastatic prostate adenocarcinoma. Glomerular filtration rate (GFR) was 13 mL/min, creatinine 4 mg/dL, and blood urea nitrogen (BUN) 58 mg/dL. The patient underwent successful image-gui...

Objective: To analyze the effect of curcumin and vitamin E on kidney function inflammatory response Wistar strain rats that received cisplatin. Material & Methods: An experimental laboratory study with a post-test only control design, using male (Rattus norwegicus). Rats were randomized simple sampling method. Samples treated cisplatin 5 mg/kg (positive group), 100 mg/kg, body, combination ...

Methods MRI was performed in 40 patients (27 males, age 62±9 years) who were scheduled for pulmonary vein isolation (PVI) and had a glomerularfiltration rate (GFR) of >30ml/min. A total of three MRIs were acquired prior to, directly after and 24 hours after PVI, using weightdependent dosages of gadolinium pententat (Gd-DPTA). 46,8±14,9 ml Gd-DPTA was given within a 3±1 day period. Renal functio...

Hemorrhagic shock (HS) following acute alcohol intoxication can increase proinflammatory cytokine production and induce marked immunosuppression. We investigated the effects of ethanol on physiopathology and cytokine levels following HS in acutely alcohol-intoxicated rats. Rats received an intravenous injection of 5 g/kg ethanol over 3 h followed by HS induced by withdrawal of 40% of total bloo...