This communication reports full genome sequencing of the bluetongue virus-1 (BTV-1) isolate MKD20/08/Ind from goat in northern India. The total BTV-1 genome size was found to be 19,190bp. A comparison study between the Indian isolate and other global isolates revealed that it belongs to the 'Eastern' BTV topotype. The full genome sequence of BTV-1 will provide vital information on its geographi...

Although bluetongue (BT) causes large numbers of sheep mortalities in some parts of the world, the main economic global impact is due to restricted trade. Australia supports a risk-based approach using current scientific knowledge to determine animal health requirements for international trade. It is important that import health conditions for bluetongue virus (BTV) are based on science and are...

(1) United States Department of Agriculture (USDA)-Agricultural Research Service (ARS), Arthropod-Borne Animal Diseases Research Laboratory, Dept. 3354, 1000 E. University Avenue, Laramie, WY 82071, United States of America (2) Present address: Centers for Disease Control and Prevention, NCID/DVRD/Special Pathogens Branch, 1600 Clifton Rd NE, Building 15-SB, Mailstop G14, Atlanta, GA 30333, Uni...

This study has determined the proportional seropositivity of two zoonotic diseases, Q fever and brucellosis, and bluetongue virus (BTV) which is nonzoonotic, in five provinces of Lao People's Democratic Republic (PDR) (Loungphabang, Luangnumtha, Xayaboury, Xiengkhouang, and Champasak, and Vientiane Province and Vientiane capital). A total of 1,089 samples from buffalo, cattle, pigs, and goats w...

The protective efficacy of recombinant vaccines expressing serotype 8 bluetongue virus (BTV-8) capsid proteins was tested in a mouse model. The recombinant vaccines comprised plasmid DNA or Modified Vaccinia Ankara viruses encoding BTV VP2, VP5 or VP7 proteins. These constructs were administered alone or in combination using either a homologous prime boost vaccination regime (rMVA/rMVA) or a he...

In mid September 2008, clinical signs of bluetongue (particularly coronitis) were observed in cows on three different farms in eastern Netherlands (Luttenberg, Heeten, and Barchem), two of which had been vaccinated with an inactivated BTV-8 vaccine (during May-June 2008). Bluetongue virus (BTV) infection was also detected on a fourth farm (Oldenzaal) in the same area while testing for export. B...

The objectives of this cross-sectional study were to determine the seroprevalence of blue tongue virus (BTV) and assess potential risk factors associated with BTV infection in dairy cattle with reproductive problems in Sudan. Serum samples were collected from a total of 784 animals from 37 herds and tested for antibodies against BTV using cELISA. A total of 663 out of 784 (84.57%) sera tested p...

Bluetongue virus (BTV) is an economically important arbovirus of ruminants that is transmitted by Culicoides spp. biting midges. BTV infection of ruminants results in a high viraemia, suggesting that repeated sharing of needles between animals could result in its iatrogenic transmission. Studies defining the risk of iatrogenic transmission of blood-borne pathogens by less invasive routes, such ...

BACKGROUND Recently much attention has been given to developing national-scale micro-simulation models for livestock diseases that can be used to predict spread and assess the impact of control measures. The focus of these models has been on directly transmitted infections with little attention given to vector-borne diseases such as bluetongue, a viral disease of ruminants transmitted by Culico...

Bluetongue (BT) is a potentially devastating midge-borne disease of ruminants that recently spread across Europe from its traditional tropical endemic areas. Historically, bluetongue virus (BTV) made only brief and rare incursions into fringe areas of Europe, with the Afro-Asian biting midge vector Culicoides imicola being largely responsible for transmission. Since 1998, however, different str...