surgery on the skeleton frequently requires harvesting of autogenous bone graft from the pelvis, but this procedure often is complicated by problems. the purpose of this retrospective, comparative descriptive study was to compare the efficacy of metal-derived bioactive glass (novabone) versus autogenous iliac crest bone graft in adolescent idiopathic scoliosis surgery. the study was carried out...

purpose: given that weight and body mass index (bmi) are considered as modifiable factors in osteoporosis, the present study aimed to examine the relationship of weight and bmi with bone mineral density (bmd) and bone mineral content (bmc) at the femur and lumbar vertebrae in perimenopausal women. methods: in this descriptive-correlational study, we measured the bone density of the femur and lu...

background different clinical and epidemiological studies using dual-energy x-ray absorptiometry have shown an increased prevalence of low bone mineral density in patients with inflammatory bowel diseases.the aim of this study was to assess the correlation between bone density and the disease activity in patients with ulcerative colitis. methods in this cross-sectional study, 52 patients with u...

background scaphoid fractures are the most common type of carpal fractures. objectives the aim of the study was to compare the diagnostic value of panoramic and conventional radiographs of the wrist in scaphoid fractures. patients and methods the panoramic and conventional radiographs of 122 patients with acute and chronic wrist trauma were studied. the radiographs were analyzed and examined by...

conclusions the outside diameter/inside diameter ratio at the metaphyseal/diaphyseal junction of the distal radius on ap radiographs is suitable for use as a predictor of distal-radius bone density. further studies should be performed, and clinical utility evaluated. results the mean bmd was 0.559 (sd = 0.236) g / cm2. the mean outside diameter/inside diameter ratio was 1.24 (sd = 0.013); the r...

the biological interaction between the jaw bones and dental implant is fundamental for the long-term success of dental implant placement. nevertheless, the insufficient bone volume remains a major clinical problem, especially in case of immediate dental implant. using a canine model, the present study proves the regenerative potential of adipose- derived stem cells (adscs) to repair peri-implan...

Development of a tumor is known to be a result of accumulation of DNA mutations in somatic cells. However, the processes of how DNA mutations are produced and how DNA mutations accumulate in somatic cells are not completely known. There are several types of DNA mutations; however point mutations are the main type of mutations that can remain and accumulate in cells. Severe DNA injuries are the ...

Lung is a complex organ lined with epithelial cells. In order to maintain its homeostasis and normal functions following injuries caused by varied extraneous and intraneous insults, such as inhaled environmental pollutants and overwhelming inflammatory responses, the respiratory epithelium normally undergoes regenerations by the proliferation and differentiation of region-specific epithelial st...

With the overall objective of assessing the potential of utilizing plasma protein binding interactions in combination with the prodrug approach for improving the pharmacokinetics of drug substances, a series of model carbonate ester prodrugs of phenol, encompassing derivatives with fatty acid-like structures, were characterized in vitro. Stability of the derivatives was studied in aqueous solut...

OBJECTIVES Several reports demonstrated that ethanol administration impairs the DNA synthesis in rat hepatocytes. Also, it has been demonstrated that prostaglandin (PG) helps prevent membrane damage by hepatotoxic chemicals. In this study, the authors examined PG's effects on the toxicity of ethanol in the primary culture of rat regenerations. METHODS We examined two kinds of parameters, i.e....