Primary stability is absence of mobility in the bone bed after mini-implant placement and depends on bone quality among other factors. Bone quality is a subjective term frequently considered as bone density. The aim of this preliminary study was to evaluate bone density in two bovine pelvic regions and verify the primary stability of miniscrews inserted into them. Forty bone blocks were extract...

BACKGROUND Recombinant human bone morphogenic protein-2 stimulates bone augmentation in animal models. The aim of this study was to evaluate the capacity of bovine bone mineral coated with synthetic oligopeptides to enhance guided bone regeneration in the beagle 3-wall defect model and the clinical implications. METHODS The second and fourth mandibular premolars of four adult beagle dogs were...

INTRODUCTION Successful graft ingrowth following reconstruction of the anterior cruciate ligament is governed by complex biological processes at the tendon-bone interface. The aim of this study was to investigate in an in vitro study the effects of bone morphogenetic protein 7 (BMP-7) on tendon-bone integration. MATERIALS AND METHODS To study the biological effects of BMP-7 on the process of ...

statement of problem: the guided bone regeneration (gbr) technique does not always produce consistent results. bone filling within the space provided by the membrane can be incomplete. purpose: the aim of this study was to evaluate the effect of a collagen membrane (bio-gide) in combination with or without deproteinezed bovine bone mineral (bio-oss) on the healing of calvarial defects in rabbit...

• Porous BPS hydrogel was fabricated. fast biomineralized using urease. The bone-like apatite formed on hydrogels. cytocompatibility of biomimeralized hydrogels improved. development with excellent is great importance for tissue engineering applications. Here, porous polyvinyl alcohol/alginate/biphasic calcium phosphate (BPS) were fabricated via chemical and physical crosslinking methods, the i...

Abstract When studying bone fragility diseases, it is difficult to identify which factors reduce bone’s resistance fracture because these diseases alter at many length scales. Here, we investigate the contribution of nanoscale collagen behavior on macroscale toughness and microscale toughening mechanisms using a bovine heat-treatment model. This model assessed by developing an in situ testing t...

AIM The cysteine protease cathepsin K (CatK), abundantly expressed in osteoclasts, is responsible for the degradation of bone matrix proteins, including collagen type 1. Thus, CatK is an attractive target for new anti-resorptive osteoporosis therapies, but the wider effects of CatK inhibitors on bone cells also need to be evaluated to assess their effects on bone. Therefore, we selected, among ...

Background: Tooth extraction is a procedure with the highest prevalence of causing alveolar bone damage. After extraction, dimension will change. This needs balance formation and resorption. Osteocytes are most common cells in have an essential role formation. study explores effect bovine tooth grafts on number osteocytes socket preservation process post-dental extraction. Methods: A total 28 W...

We have developed a solid-phase competitive radioimmunoassay for human osteonectin, using a monoclonal antibody to bovine osteonectin. The assay is both specific and sensitive, being capable of measuring as little as 10 ng of osteonectin. Osteonectin measurements in parallel serum and plasma samples obtained from healthy individuals showed the plasma level to be 0.9 microgram/ml, while that of ...