Nowadays, head injuries are becoming more frequent in children. The most common cause of head injuries in children is fall, and, in more severe injuries, traffic accident trauma. In traumatic brain injuries in infants and small children, the most common symptoms are paleness, somnolence and vomiting, the so called “pediatric contusion syndrome”. After the first year of age, light head trauma oc...

Background: Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from severe ischemia/reperfusion (I/R) injuries. This study evaluated the impacts of post-ischemic inhibition of ACE, enalapril, on brain inf...

Ischemic stroke accounts for about 87 percent of all cases. It occurs as a result of an obstruction within a vessel of the brain and sudden loss of blood circulation to the corresponding area resulting in the loss of brain function. It is caused by thrombotic or embolic occlusion of an artery and is more common than hemorrhagic stroke. We know that most of the injuries after an acute ischemic s...

Traumatic brain injuries remain a 21 century scourge that remains subterranean and mostly invisible in our societies. Integrated care systems for traumatic brain injury patients effectively integrate the key systemic components horizontally and vertically so as to improve patient outcomes and systemic performance. This review paper briefly identifies the nature of traumatic brain injuries in Ca...

Traumatic brain injuries often lead to severe disability or death. These injuries most often affect younger, more active people and are likely to have enduring physical, emotional, and financial costs. In order to determine the incidence, etiology and severity of traumatic brain injuries in Alaska, the Alaska Department of Health and Social Services has conducted a three-year study of the demog...