Background and purpose: Despite the high prevalence of chronic obstructive pulmonary disease, There haven,t been definite curative treatment for the disease and focus of treatment has directed towards pulmonary rehabilitation as an effective non-drug treatments. this study were performed to determine the effect of motivational abdominal breathing device on breathing pattern and dyspnea of chron...

background: application noninvasive ventilation in the patients with exacerbation of chronic obstructive pulmonary disease (copd) reduced mortality. this case-control study was designed to compare efficiency and outcome of non-invasive (niv) versus invasive positive pressure ventilation (ippv) in respiratory failure due to copd methods: the patients were assigned to niv or ippv intermittantly.t...

BACKGROUND AND OBJECTIVES In children undergoing congenital heart surgery, plasma brain natriuretic peptide levels may have a role in development of low cardiac output syndrome that is defined as a combination of clinical findings and interventions to augment cardiac output in children with pulmonary hypertension. METHODS In a prospective observational study, fifty-one children undergoing con...

INTRODUCTION Congestive heart failure (CHF) is a common disease and its prevalence is increasing in industrialized countries. NT-proBNP measurement is an established diagnostic test for diagnosis of CHF in patients who present to emergency room with acute dyspnea. The primary object of this study was to determine the relationship between levels of brain natriuretic peptide precursor and severit...

1. Brain natriuretic peptide is a new natriuretic hormone with striking similarity to atrial natriuretic peptide, but there are no previous data concerning its clearance in man. Two pathways of clearance for atrial natriuretic peptide are recognized: degradation by neutral endopeptidase and binding to atrial natriuretic peptide clearance receptors. We have examined the effect of candoxatril, an...

I thank Lippi and Targher for their kind remarks about my editorial in CHEST (February 2008),1 which describes “tricks of the trade” for assessing pulmonary embolism prognosis. They raise two important questions: (1) Should measurement of natriuretic peptides such as brain natriuretic peptide or pro-brain natriuretic peptide be incorporated into routine prognostic assessment of acute pulmonary ...

Pulmonary hypertension (PH) is an important cause of heart failure in chronic obstructive pulmonary disease (COPD). The pro brain natriuretic peptide N-terminal (NT-proBNP) has been suggested as a noninvasive marker to evaluate ventricular function. However, there is no evidence to support the use of NT-proBNP in monitoring the benefits of vasodilators in COPD induced PH. Thus, we used NT-proBN...

the aim of the study was to evaluate the clinical usefulness of n-terminal pro-brain natriuretic peptide (nt-pro bnp) and nitric oxide (no) with echocardiography (gold standard test) in diagnosis of canine cardiomyopathy. out of 374 cases, 82 cases showing cardiovascular abnormalities including 16 cases of cardiomyopathy were further selected for standardization of biomarkers. significant (p

background: serum n-terminal pro-brain natriuretic peptide (nt-probnp), a polypeptide secreted by ventricular myocytes in response to stretch, was suggested as a predictor of adverse prognosis of the acute coronary syndrome (acs). we examined the association between nt-probnp level and angiographic findings in acs patients to determine whether it could be used as a predictor of the severity of ...

background: brain type natriuretic peptide (bnp) is a cardiac hormone that is secreted mainly by the ventricles in response to volume expansion and pressure load. it can predict post-operative complications after heart surgery in adults. we sought to investigate the prognostic value of bnp in children after heart surgery. methods: we measured the bnp serum levels in 96 children with congenital ...