synchronous cancer is referred to two or more histological distinct malignancies diagnosed during the same hospital admission. globally more than 1 million people get colorectal cancer yearly resulting in about 0.5 million deaths. vulvar cancer is the fourth most common gynecologic cancer (following the corpus uterine cancer, cancer of ovary and cervix) and comprises only 4 percent of malignanc...

This study aims to investigate the contribution of diagnostic exposures to the rising rates of brain tumours and other neoplasms which are observed in several industrial nations. Included are benign tumours in the head and neck region and cataracts which are neglected in usual risk estimates by international and national radiation protection committees. Dose-effect relationships for tumours of ...

Hypoxia is known to be an important prognostic marker in many human cancers. We report the use of two oxygen measurement techniques in human brain tumors and compare these data with semiquantitative histological end points. Oxygenation was measured using the Eppendorf needle electrode and/or EF5 binding in 28 brain tumors. These data were compared with necrosis, mitosis, and endothelial prolife...

Tumefactive demyelinating brain disease can pose a diagnostic challenge in patients without a pre-existing diagnosis of multiple sclerosis by mimicking intra-cranial neoplasms, infarction, as well as infections. Choosing when to biopsy a tumefactive lesion to exclude alternative pathology can be difficult. Here we report a case of a 44 year old female patient without a previous history of multi...

PRIMARY BENIGN and malignant brain tumors are common and occur with an incidence of 12.8 cases per 100,000 according to the Central Brain Tumor Registry of the United States. The relative incidence of brain tumors is age dependent. Intracranial neoplasms, or new tissue growths, represent the most common solid tumors in children younger than age 15. In this age group, primary tumors of the nervo...