In this paper, we report on the crystal structure of salt 1-(4-bromo-2,3,5,6-tetrafluorophenyl)-3-(3-phenylbenzyl)-4-methylimidazolium bromide, 3, synthesized by sequential nucleophilic attack 4-methylimidazole bromopentafluorobenzene and then 3-phenylbenzyl bromide. The was characterized 1H, 13C, 19F NMR spectroscopy mass spectrometry.

Key words : Methyl bromide—EEG—Wakefulness—Non-REM sleep—REM sleep— Bromine ions—Methanol Methyl bromide has been widely used as a fumigant in plant quarantine and agriculture, because of its strong insecticidal effect.1) However, methyl bromide is known to impair the function of the central nervous system (CNS) , when workers are exposed to it through inhalation and dermal contact. Disorders o...

forty-five patients with chronic obstructive pulmonary disease were studied to compare the acute effects of ipratropium bromide (60 µg), salbutamol (300 µg) and placebo (3 puffs) on the forced expiratory volume in 1 sec (fev 1) and forced vital capacity (pvc). ipratropium bromide produced a significantly greater improvement than salbutamol in both fev1 and fvc at 15,60 and 180 minutes after dru...

N-isopropyltheobromine and N-sec-butyltheobromine were synthesized via nucleophilic substitution reaction by reacting theobromine and two kind of alkyl bromide derivatives, i.e. isopropyl bromide and sec-butyl bromide using N, Ndimethylformamide (DMF) as a solvent. Yields (N-isopropyltheobromine = 7.70%; N-sec-butyltheobromine = 5.89%) were slightly less than the previous synthesis which used e...

DESCRIPTION The active ingredient in ATROVENT (ipratropium bromide) Inhalation Aerosol is ipratropium bromide. It is an anticholinergic bronchodilator chemically described as 8azoniabicyclo[3.2.1]-octane, 3-(3-hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1methylethyl)-, bromide, monohydrate (endo,syn)-,(±): a synthetic quaternary ammonium compound chemically related to atropine. The structural fo...