The observation that ABO agglutinins are present in a wide variety of pollens (Denborough, 1964) and so must commonly be inhaled, and the knowledge that plant agglutinins are antigenic (Mikela, 1957), prompted us to study secretor status in allergic disease of the respiratory tract, namely in asthma and hay fever. The opportunity has been taken to measure the amount of isoagglutinins present in...

In the last number of the Gazette Pasricha, Panja and Lai (1936) recorded the results of an investigation into the frequency and concentration of agglutinins for the enteric group of organisms in sera collected from 280 Indian patients admitted into the Carmichael Hospital for Tropical Diseases. These sera were also used for the estimation of agglutinins for the proteus X strains X19, X2 and XK.

A previous study (15) has shown tha t transplantable mouse tumors differ in their capacity to grow progressively in rats pretreated with lyophilized mouse tumor tissue. An inverse correlation was found between the degree of strain specificity of tumors in mice and their transplantability to Pretreated rats. The present study deals with the correlation found between the transplantability of mous...

Reliability of the Widal tube agglutination test has been the subject of many controversies over the years. This study was performed to assess the effect of certain modifications on the performance of Widal test in a novel microplate assay. Sera from 37 patients (21 males; 16 females) (mean age 28 +/- 7 years) were tested in the Immunology Unit at King Khalid University Hospital, Riyadh. Among ...

Brucella is a Gram-negative, facultative intracellular bacterium that causes zoonotic brucellosis in humans and various animals. Out of 10 classified Brucella species, B. melitensis, B. abortus, B. suis, and B. canis are pathogenic to humans. In the past decade, the mechanisms of Brucella pathogenesis and host immunity have been extensively investigated using the cutting edge systems biology an...

The phenomenon of in vitro platelet clumping and consequent pseudothrombocytopenia in the presence of EDTA was studied in the plasmas and sera of three patients. A heterogeneity was identified among these platelet agglutinins. lgG agglutinins present in two patients recognized antigens that were present when EDTA was added to platelets. This effect of EDTA did not appear to be mediated by calci...

BACKGROUND Brucellosis is a zoonosis that occurs worldwide. The disease has been completely eradicated in livestock in Sweden in 1994, and all cases of confirmed human brucellosis are imported into Sweden from other countries. However, due to an increase in the number of refugees and asylum seekers from the middle-east to Sweden, there is a need to improve the current diagnostic methodology for...

Freeman, Bob A. (The University of Chicago, Chicago, Ill.), and Barry H. Rumack. Cytopathogenic effect of Brucella spheroplasts on monocytes in tissue culture. J. Bacteriol. 88:1310-1315. 1964.-Mononuclear phagocytes from guinea pig peritoneal exudates were shown to ingest both normal Brucella suis and spheroplasts prepared from B. suis by treatment with glycine and with penicillin. Quantitativ...

BACKGROUND Many serological tests have been used for the diagnosis of human brucellosis. A new serological method is identified as Brucella Coombs gel test based on the principle of centrifugation gel system similar to the gel system used in blood group determination. In this system, if Brucella antibodies were present in the serum, antigen and antibody would remain as a pink complex on the gel...

Brucellosis is caused by infection with Brucella species and exhibits diverse clinical manifestations in infected humans. Monocytes and macrophages are not only the first line of defense against Brucella infection but also a main reservoir for Brucella. In the present study, we examined the effects of Brucella infection on human peripheral monocytes and monocyte-derived polarized macrophages. W...