A 12 year old boy suffering from p67-phox deficient chronic granulomatous disease presented with a bullous skin disease and a lung infection with paecilomyces species. The histopathology of a bullous lesion showed subepidermal blister formation and microabcesses containing eosinophils in the dermal papillae. By direct immunofluorescence, linear staining of IgA at the dermal-epidermal junction w...

Pemphigus herpetiformis is an autoimmune bullous disease, that combines clinical features of dermatitis herpetiformis and linear IgA bullous dermatosis and immunological characteristics of pemphigus, which makes this disease peculiar and this diagnosis rarely suspected in the first evaluation of the patient. The reported case is of a patient with clinically bullous disease similar to dermatitis...

BACKGROUND Post-vaccination infantile bullous pemphigod is a rare presentation. CASE CHARACTERISTICS A 2-month-old girl presented with widespread bullae, erosions, necrotic and targetoid lesions over body and mucosae after vaccination. Histology and direct immunofluorescence (DIF) were consistent with bullous pemphigoid. INTERVENTION Clinical remission with oral steroids and no recurrence w...

Bullous pemphigoid is an autoimmune sub epidermal blistering dermatosis that is uncommon in childhood. We report two cases of children with bullous pemphigoid. The first one was a case of a 4-month-old female infant, whereas the second is of a 3-month-old male infant. The two cases presented clinical and laboratory data for the confirmatory diagnosis of bullous pemphigoid. Opportunely we review...

BACKGROUND Linear IgA bullous dermatosis of childhood is a rare autoimmune bullous disease that mainly affects preschool-aged children. Dapsone is considered the first-line therapy with prompt response from most patients. However, it may be contraindicated in certain conditions such as glucose-6-phosphate dehydrogenase deficiency. OBJECTIVE We sought to assess the efficacy of flucloxacillin i...

Vesico-bullous subacute cutaneous lupus erythematosus is an uncommon and severe presentation. The authors report an exuberant case of vesico-bullous subacute cutaneous lupus erythematosus successfully treated with dapsone and hydroxychloroquine.

OBJECTIVES To identify and analyze trends in bullous disease mortality from 1979 through 2002 in the United States. DESIGN Retrospective population-based analysis. SETTING Mortality records from the Centers for Disease Control and Prevention mortality database. PARTICIPANTS Mortality records from 1979 through 2002 for persons who died of bullous disease. MAIN OUTCOME MEASURES Age-adjust...