The African green monkey has previously been found to be a promising model for the study of atherosclerosis. We have compared the plasma and HDL cholesterol response to dietary manipulation in the two subspecies of African green monkeys (vervets and grivets) most often imported for biomedical research purposes. Twenty vervets and 20 grivets were fed, in succession, diets containing safflower oi...

The aim of this study was to optimize the lipsticks formulation according to the physical properties and sensory attributes and investigate the relationship between instrumental and sensory analyses and evaluate the influence of the main ingredients, beeswax and oil, with analysis of lipsticks properties. Central composite design was used to optimize the mixture of oils and beeswax and cocoa bu...

Lipid-based nutrient supplements (LNS) are used to prevent and treat moderate and severe acute malnutrition, a leading cause of mortality in children-under-five. The physical and chemical changes of two new LNS products were evaluated before and after accelerated shelf life testing (ASLT) according to protocols suggested by the U.S. Agency for International Development (USAID) and Doctors witho...

Wistar rats were fed various atherogenic diets containing 5% cholesterol, 0.3y0 thiouracil, 2y0 bile salt, and 40% fat (butter, corn oil, peanut oil, or medium-chain triglycerides (MCT)). Blood specimens were obtained weekly for counting lipid-laden leukocytes (lipophages) and serum cholesterol levels were determined. The lipophages in circulating blood were defined as leukocytes, usually monoc...

This study was designed to determine the effects of a variety of naturally occurring saturated fats on aortic lesion formation in C57BL/6J mice that are susceptible to diet-induced fatty streak lesions. Groups of female mice were randomly assigned to one of seven treatment groups and were fed diets containing 15% (w/w) hydrogenated coconut oil, hydrogenated soy oil, hydrogenated palm oil, cocoa...

AIMS Postprandial triglyceride-rich lipoproteins (TRL) have a direct effect on vascular smooth muscle cells (SMC) and they increase the risk of atherogenesis. Here, we have tested the hypothesis that the different fatty acid composition of TRL is capable of differentially modifying gene expression in human coronary artery SMC (CASMC). In addition, the effect of TRL on cell proliferation and tra...