The anthocyanins (1-3) and cyanidin isolated from tart cherries exhibited in vitro antioxidant and antiinflammatory activities comparable to commercial products. The inhibition of lipid peroxidation of anthocyanins 1-3 and their aglycon, cyanidin, were 39, 70, 75, and 57%, respectively, at 2-mM concentrations. The antioxidant activities of 1-3 and cyanidin were comparable to the antioxidant act...

Few protein biomarkers for oxidative stress have been reported. In this study, we attempted to identify the proteins selectively overexpressed in human colon tumor cells by treating with hydrogen peroxide as oxidative stress. A proteomic analysis followed by western blotting showed that phosphoglycerate kinase 1 (PGK1) was induced by hydrogen peroxide in a dose-dependent manner, while its expre...

In this study, ethanol extract of Carthamustinctoriuswas studied for superoxide anion scavenging activity. The antioxidant properties of Carthamustinctorius ethanol extract was evaluated using superoxide anion radical scavenging activities. The extract of Carthamustinctorius exhibited strong total antioxidant activity and superoxide anion scavenging activity. This antioxidant activity test were...

In generally, bioactive compounds are named functional compounds. There is trend to investigate of isolation, identification and biological activities of functional compounds from natural sourcs in recent years. The aim of this work is to investigate functional compounds analysis and their antioxidant capacity of cherry laurel seed. In this work some functional compounds were isolated by chroma...

The case of a 17 year old abuser of butane aerosols who developed fulminant hepatic failure after taking a proprietary engine or carburetor cleaner is described. Fatalities as a result of liver failure due to volatile hydrocarbons or solvents have not previously been reported. The likely toxins included isopropyl alcohol, methyl amyl alcohol, butylated hydroxytoluene as well as petroleum produc...

A novel flavonoidic compound, 3,5-dihydroxy-4’,7-dimethoxyflavone, has been isolated from the rhizomes of Zingiber phillipseae. The dichloromethane extract of this species was shown to be non-toxic with LC50 for acute and toxic levels at 9,732 ppm and 562 ppm, respectively. The extract showed higher antioxidant activity than the standard (butylated hydroxytoluene, BHT) but lower than dichlorome...

Ferritin and haemosiderin were shown, by the measurement of malondialdehyde production and loss of polyunsaturated fatty acids, to stimulate lipid peroxidation in liposomes. At pH 7.4 ascorbate was additionally required to achieve peroxidation; however, peroxidation occurred at pH 4.5 in the presence of iron-proteins alone. The damage was completely inhibited by the incorporation of chain-break...

This study presents antibacterial activity of several organic metabolites produced by a fish pathogen, Acinetobacter sp. strain An 2, from marine ecosystem of Goa. Cell extract demonstrated stronger inhibitory effects on Gram negative bacteria as compared to common antibiotics. GC-MS analysis of crude cell extract revealed presence of potential antimicrobials (butylated hydroxytoluene, phenol, ...