Most studies designed to determine the etiologic agent in byssinosis have relied on in vitro test for normal volunteers to assess the effects of components isolated from cotton plants, cotton factory dust, or their associated organisms. In one of the few studies directly on byssinotic subjects, symptoms were reproduced on inhalation challenge with a condensed polyphenol isolated from bracts ofe...

If is an appropriate time to review chronic non-tuberculous chest disease (C.N.T.C.D.). This is now one of the most important medical diseases. It is extremely common. The disability is often gross. The mortality is heavy. It can now be observed without the confusion of co-existing phthisis and without its course being cut short by broncho-pneumonia. The old background of poverty and malnutriti...

A report of the gross and microscopic appearances in the lungs and the weights of the cardiac ventricles in 43 subjects receiving industrial benefit for byssinosis is presented. In 27 (63%) there was no significant emphysema, in 10 (23%) there were varying amounts of centrilobular emphysema, and panacinar emphysema was found in six (14%). Other changes were of non-specific nature, but most case...