Objectives: Cow urine ark (CUA), known as “Amrita” as mentioned in Ayurveda, contains‎ anti-hyperglycemic and antioxidant effects. Therefore, we designed the present study to evaluate the lipid ‎lowering activity of CUA and its possible implication in metabolic syndrome.‎ Materials and Methods: Thirty guinea pigs of either sex were divided into five groups: Group 1 and 2 serving as a vehicle ‎a...

High-density lipoprotein-cholesterol (HDL-C) is one of the most commonly measured biomarkers integrated into public health prevention guidelines. Major epidemiological studies have demonstrated strong, inverse, and independent relationships between HDL-C and cardiovascular disease (CVD) and stroke. However, several recent clinical trials have challenged the value of raising HDL-C pharmacologica...

To evaluate the impact of low levels of high density lipoprotein cholesterol (HDL-c) on patients with LDL-c average levels, focusing on oxidative, lipidic, and inflammatory profiles. Patients with cardiovascular risk factors (n = 169) and control subjects (n = 73) were divided into 2 subgroups, one of normal HDL-c and the other of low HDL-c levels. The following data was analyzed: BP, BMI, wais...

CONTEXT Cardiovascular disease (CVD) is the largest cause of mortality in Indians. Insulin resistance and related dyslipidemia of increased triglyceride (TG), small dense low-density lipoprotein (sd-LDL) particles, and decreased high-density lipoprotein-cholesterol (HDL-C) are associated with increased risk of CVD. TG/HDL-C ratio could be a potential surrogate marker for this South Asian phenot...

abstract   background: obesity is directly related to dyslipidemia which contributes significantly to the risk of coronary heart disease, a major cardiovascular disease and a serious health problem. the aim of this study was to compare the effects of low calorie diet and those of lovastatin on serum lipoproteins, apo b, homocysteine, and total antioxidant capacity (tac) in hyperlipidemic obese ...

High-density lipoprotein (HDL) cholesterol has been known for ages to be cardio-protective due its defensive action against genesis of atherosclerosis. Increasing the serum HDL (HDL-C) as a prospective potential prevent coronary heart disease could not prove beneficial in human trials that put forward major concern about role and functional contribution HDL-C health. Many observational studies ...

AIM Since we previously reported that lower levels of HDL-C may be most useful for predicting coronary artery disease (CAD) as assessed by multi-detector row computed tomography (MDCT), we sought to confirm, among the levels of LDL-C, HDL-C, non-HDL-C (total cholesterol minus HDL-C) and the ratio of LDL-C to HDL-C (LDL-C/HDL-C), which is most closely related to the presence of CAD. METHODS AN...

BACKGROUND Recent data suggest that an increased level of high-density lipoprotein cholesterol (HDL-C) is not causally protective against heart disease, shifting focus to other sub-phenotypes of HDL. Prior work on the effects of dietary intakes has focused largely on HDL-C. The goal of this study was to identify the dietary intakes that affect HDL-related measures: HDL-C, HDL-2, HDL-3, and apoA...

Background. There is to our knowledge metabolic changes induced by combined oral contraceptives (COC) use in regularly active females. Objectives. Analyzing blood cortisol and other biochemical variables in active (COC) users and non-users. Methods. A total of 123 active female students (25 COC users and 98 non-users) volunteered to participate in the study.  The COC users declared 2-3 years ...