Production and characterization of soft cross-linked gelatin sponge by using glutaraldehyde for blood hemostasis application, is the goal of this study. Biodegradable hydrogels were prepared through crosslinking of gelatin with glutaraldehyde followed by freeze drying. The effects of gelatin concentration, amount of crosslink agent and freeze drying temperature on mechanical properties and...

The purpose of this research was to formulate and systematically evaluate in vitro performances of chitosan microspheres containing Mitomycin-C. Chitosan microspheres containing Mitomycin-C were prepared by simple emulsification phase separation technique using glutaraldehyde as a cross-linking agent. Results of preliminary trials indicate that volume of cross-linking agent, time for cross-link...

Fancc suppresses cross-linker–induced genotoxicity, modulates growth-inhibitory cytokine responses, and modulates endotoxin responses. Although loss of the latter function is known to account for endotoxininduced marrow failure in murine Fancc (mFancc)–deficient mice, some argue that cytokine and endotoxin hypersensitivities devolve simply from genomic instability. Seeking to resolve this quest...

A thorough assessment of gelation progress requires real-time recording biopolymer kinetics. In this study, an in situ investigation with a customized parallel-plate rheometric setup examines how the initial distribution CaCl2 to alginate through micro-holes affects process. At constant volume and concentration reactants, stiffer gels are produced at same probing time by increasing number suppl...

PURPOSE The purpose of this research was to established new polysaccharide for the colon targeted drug delivery system, its formulation and in vitro and in vivo evaluation. METHODS Microspheres containing pectin and bora rice were prepared by ionotropic gelation technique using zinc acetate as cross linking agent and model drug used was glipizide. A 3(2) full factorial design was employed to ...

While inward remodeling of small arteries in response to low blood flow, hypertension, and chronic vasoconstriction depends on type 2 transglutaminase (TG2), the mechanisms of action have remained unresolved. We studied the regulation of TG2 activity, its (sub) cellular localization, substrates, and its specific mode of action during small artery inward remodeling. We found that inward remodeli...

Research on the effect of cellulose and kaolin addition to alginate-cellulose-kaolin composites' characteristics as a slow-release agent urea fertilizer has been done. The technique used in preparation is an extrusion using 2% CaCl2 solution cross-linker. compositions were varied determine their such diameter, color, swelling ratio, entrapment efficiency, release urea. results showed that diame...

Natural Zn reserves might be exhausted in the following decades. Electric arc furnace (EAF) dust is an essential secondary resource. The recovery of from EAF a critical factor sustainable development industry and steelmaking industry. Efficient destruction ZnFe2O4 crystal structure separation Fe are key issues to recycle dust. Molten metal chlorides believed effective breaking ZnFe2O4. This wor...

lidocaine (lc) is a local anesthetic agent. the aim of this study was to prolong the anesthetic effect of this drug in the oral cavity in the treatment of oral mucositis. films of lc were prepared with three different molecular weights (mw) of chitosan in three different concentrations (1-3%) and were then cross-linked by solvent casting evaporation method with tripolyphosphate penta sodium sal...