NAD-dependent glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a ubiquitous enzyme involved in the glycolytic pathway. It has been widely demonstrated that mammalian GAPDH, in addition to its role in glycolysis, fulfills alternative functions mainly linked to its susceptibility to oxidative posttranslational modifications. Here, we investigated the responses of Arabidopsis (Arabidopsis thali...

background edible salt is the most commonly used food additive worldwide. therefore, any contamination of table salt could be a health hazard. objectives the present study aimed to determine the levels of heavy metals in table and bakery refined salts. materials and methods eighty-one table refined salt samples and the same number of bakery refined salt samples were purchased from retail market...

Cadmium (CdCl2) is one of the most prevalent environmental and biologically hazardous toxicants among metals. This study was carried out to evaluate the ameliorative role of Grape seed extract (GSE) on CdCl2 induced spleen toxicity in adult male albino rats. Forty adult male albino rats were equally divided into 4 groups. Group I (control); group II, administered GSE at dose 100 mg / kg bw/ day...

BACKGROUND Improved chemical hazard management such as REACH policy objective as well as drug ADMETOX prediction, while limiting the extent of animal testing, requires the development of increasingly high throughput as well as highly pertinent in vitro toxicity assays. METHODOLOGY This report describes a new in vitro method for toxicity testing, combining cell-based assays in nanodrop Cell-on...

Cadmium ions influence on the content of anthocyanins as non-plastid pigments and the activity of phenylalanine ammonia-lyase (EC 4.3.1.24) as primary enzyme of their biosynthesis in two lettuce varieties (Lactuca sativa L.) with different anthocyanin content was investigated. The increases in anthocyanin content and enzymatic activity of phenylalanine ammonia-lyase of both lettuce plant variet...

Cadmium is a dangerous occupational and environmental toxin. It accumulates in the human organism mainly in liver and kidneys. Cadmium half-life is about 10 years, so the symptoms of cadmium intoxication may occur several years after the exposure. Until now in treating intoxication with this metal chelating compounds have been used, burdened with numerous undesirable symptoms. In our investigat...

Chloride (Cl-) has been related to increased phytoavailability of cadmium (Cd) in soil. A glasshouse experiment using a historically contaminated soil was undertaken to evaluate the effect of chloride on Cd uptake by salt-tolerant plants and possibly quantify the uptake of discrete Cd species (e.g. Cd2+, CdCl+, CdCl(0)2). Chloride treatments were applied as 100 mM NaCl and compared with equival...

sulforaphane is a strong anticarsenogen compound which is produced in broccoli. it seems salt stress improves sulforaphane production via systemic acquired resistance. to obtain suitable salt concentration and for having more content of sulforaphane with controlling germination percentage, nacl in 5 levels 0, 50, 100, 150, 200 mm (0, 4.53, 9.125, 13.68, 18.25 ds/m ) and salicylic acid in 3 leve...

The rare earth metals cerium, lanthanum, and neodymium each were evaluated in an in vitro cytotoxicity assay system using adult, male Sprague-Dawley rat pulmonary alveolar macrophages. Both the soluble chloride form of these metals and their insoluble metal oxides were studied. For comparison purposes, the cytotoxicities of cadmium chloride and cadmium oxide were also quantified in this test sy...