Actinic Keratoses (AKs) are premalignant intraepithelial skin lesions that can progress to cutaneous squamous cell carcinoma (SCC). The field of cancer immunotherapy has demonstrated the ability immune system treat late-stage cancers. We have shown also be leveraged prevent through a randomized, double-blind clinical trial. Topical calcipotriol plus 5-fluorouracil (5-FU) effectively eliminates ...

A 56-year-old man with chronic hepatitis C was treated with pegylated interferon alfa-2a in combination with ribavirin. However, psoriatic lesions appeared and worsened dramatically during therapy. Because of the extensive skin eruptions, he stopped therapy for chronic hepatitis C and subsequently started narrow-band ultraviolet B phototherapy and topical calcipotriol/betamethasone dipropionate...

of the hair follicles) and differentiates it from the other conditions.5 Histology of tissue obtained by curettage of a papule is sufficient to establish the definitive diagnosis. Although there are reports of GP that resolved spontaneously once the irritant was eliminated, the lesions usually persist. A number of therapeutic modalities, including topical and oral preparations of retinoids, vit...

BACKGROUND Psoriasis causes worldwide concern because of its high-prevalence, as well as its harmful, and incurable characteristics. Topical therapy is a conventional treatment for psoriasis vulgaris. Chinese medicine (CM) has been commonly used in an integrative way for psoriasis patients for many years. Some CM therapies have shown therapeutic effects for psoriasis vulgaris (PV), including re...

Porokeratotic eccrine ostial and dermal duct nevus (PEODDN) is an uncommon, benign dermatosis and is characterized by asymptomatic grouped keratotic papules and plaques with a linear pattern on the extremities. Various treatments, including topical steroids, topical calcipotriol, topical 5-fluorouracil, retinoid, cryotherapy, and carbon dioxide laser ablation have been tried for PEODDN, but the...

The speaker gave a brief review of published reports on the medical therapy of vitiligo in the last five years. First of all, the use of topical agents was discussed. Fifty percent of the patients had more than 75% of their lesions repigmented after 0.1% tacrolimus treatment. The efficacy was comparable to clobetasol propionate. There was limited data on pimecrolimus but a trial showed that its...

A new compound product containing calcipotriol 50 nanograms per gm and betamethasone dipropionate 0.5mg per gm (Dovobet, LEO Pharma) in an ointment base was recently introduced in Canada for the treatment of psoriasis. Known as Daivobet in Europe, it was introduced to the Danish Market in 2001, and approved for marketing by the European Union. This compound has been shown to be more active than...