Under ischemic conditions, contractile responses of canine coronary artery smooth muscle are decreased, pH is decreased, and lactate levels are increased. To investigate whether lactate has a pH-independent relaxant action on contractility, inhibitory effects of 1.0 mM lactate on Ca fluxes and increased tension elicited with either 60 mM KCl or 10 ftyi prostaglandin F2o (PGF2o) were measured at...

Under ischemic conditions, contractile responses of canine coronary artery smooth muscle are decreased, pH is decreased, and lactate levels are increased. To investigate whether lactate has a pH-independent relaxant action on contractility, inhibitory effects of 1.0 mM lactate on Ca fluxes and increased tension elicited with either 60 mM KCl or 10 ftyi prostaglandin F2o (PGF2o) were measured at...

Two porous, chiral metal-organic frameworks (MOFs), Ca14(l-lactate)20(acetate)8(C2H5OH)(H2O) (MOF-1201) and Ca6(l-lactate)3(acetate)9(H2O) (MOF-1203), are constructed from Ca2+ ions and l-lactate [CH3CH(OH)COO-], where Ca2+ ions are bridged by the carboxylate and hydroxyl groups of lactate and the carboxylate group of acetate to give a three-dimensional arrangement of Ca(-COO, -OH) polyhedra su...

The impacts of AMD pollution on biological systems are mostly severe and the problem may persist from many decades to thousands of years. Consequently AMD prior to being released into the environment must be treated to meet government standards for the amount of metal and non-metal ions contained in the water. One of the best available technologies for the removal of metals from AMD is precipit...

This study was conducted to assess the effects of 0.5% Preservative Mixture (PM) containing calcium lactate (40%), sodium diacetate (40%) and sodium chloride (20%) on the microbiological, chemical and sensory quality of chicken meat nuggets stored at 4±2 C and under Modified Atmosphere Packaging o (MAP). There were two experimental groups of samples, namely control and PM-treated. The results s...

Intramuscular acidosis is a contributing factor to fatigue during high-intensity exercise. Many nutritional strategies aiming to increase intra- and extracellular buffering capacity have been investigated. Among these, supplementation of beta-alanine (~3-6.4 g/day for 4 weeks or longer), the rate-limiting factor to the intramuscular synthesis of carnosine (i.e. an intracellular buffer), has bee...

The adequate stimuli and molecular receptors for muscle metaboreceptors and nociceptors are still under investigation. We used calcium imaging of cultured primary sensory dorsal root ganglion (DRG) neurons from C57Bl/6 mice to determine candidates for metabolites that could be the adequate stimuli and receptors that could detect these stimuli. Retrograde DiI labeling determined that some of the...

In this work, fabrication of gold coated glass substrate, growth of ZnO nanorods and potentiometric response of lactic acid are explained. The biosensor was developed by immobilizing the lactate oxidase on the ZnO nanorods in combination with glutaraldehyde as a cross linker for lactate oxidase enzyme. The potentiometric technique was applied for the measuring the output (EMF) response of l-lac...

This research was carried out to evaluate the relationship between incorporation of calcite precipitation bacteria, sporosarcina pasteurii using calcium lactate as nutrient source and properties calcined clay limestone powder blended self-compacting concrete. Ten mixes were designed designated S0 S9 with control (without bacteria nutrient) S1 at varying concentrations effect cell density concen...