BACKGROUND/AIMS Recent studies have indicated that CD38 gene deficiency results in dedifferentiation or transdifferentiation of arterial smooth muscle cells upon atherogenic stimulations. However, the molecular mechanisms mediating this vascular smooth muscle (SMC) phenotypic switching remain unknown. Methods & RESULTS In the present study, we first characterized the phenotypic change in ...

Clinicohistopathological staging is insufficient to predict disease progression and clinical outcome in lung carcinoma. Based on the results of the principal component analysis of 24 samples of early-stage lung adenocarcinoma, two subgroups were identified within the early-relapse group. The histological classification of all samples of group A was poorly differentiated, whereas one out of thre...

During the vast trend of urbanization, mobile sensing in metropolitan area has become an emerging fashion and prevailing technology to monitor the environmental changes and human activities in the city scale. In this paper, we propose a novel framework, namely, the Context-Aware Metropolitan Sensing (CAMS), to rise to the increasing challenges in context acquisition, context fidelity, context d...

Cell adhesion molecules (CAMs) have essential roles in forming functional networks in the nervous system. CAMs can be classified into several families including immunoglobulin super family (IgSF), cadherin family, integrins and selections [1]. Neuroplastins are transmembrane glycoprotein’s that belong to IgSF. Neuroplastin65 (NP65) and neuroplastin55 (NP55) are produced by NPTN gene by alternat...

Content Addressable Memories or CAMs are popular parallel matching circuits. They provide the capability, in hardware, to search a table of data for a matching entry. This functionality is a high performance alternative to popular software-based searching schemes. CAMs are typically found in embedded circuitry where fast matching is essential. This paper presents a novel approach to CAM impleme...

A growing body of literature indicates that suicidal patients differ from other psychiatric patients with respect to specific psychological vulnerabilities and that suicide-specific interventions may offer benefits beyond conventional care. This naturalistic controlled-comparison trial (n = 52) examined outcomes of intensive psychiatric hospital treatment (mean length of stay 58.8 days), compar...