In cats anesthetized with pentobarbital, 188 direct microvascular pressure and diameter measurements were made of the tenuissimus muscle. The microvascular pressure in arterioles of 70 mum in diameter or larger was proportional to the systemic arterial pressure (PA). The arterioles with diameter-s ranging from 35 to 20 mum have been shown to be the principa-l source of arteriolar resistance reg...

introduction pulmonary hypertension is common among patients with hyperthyroidism, and graves’ disease constitutes the most common cause of thyrotoxicosis. case presentation we report the case of a female patient admitted to the cardiology department with shortness of breath and pretibial myxedema. the diagnostic work-up revealed combined pre- and post-capillary pulmonary hypertension due to gr...

The coronary capillary ow is analyzed theoretically based on continuum mechanics. The capillary is a long, elastic and permeable vessel loaded externally by tissue pressure. It is subject to possible periodic length changes, together with adjacent myocites. Capillary ow is driven by arteriolar-venular pressure di erence. Ultra ltration, due to transmural hydrostatic and osmotic gradients is inc...

BACKGROUND.: Hypertrophic cardiomyopathy (HCM) is characterized by asymmetric LV hypertrophy (LVH) and impairment in diastolic function. We assess the relationship between LVH and invasive indexes of diastolic function. METHODS.: 21 HCM patients underwent cardiac catheterization to assess pulmonary capillary wedge pressure, LV end-diastolic pressure (measured by microtip catheters), and LV vol...

Factors determining the symptoms of breathlessness and fatigue in patients with congestive heart failure were investigated by comparing the response to slow and fast exercise. Symptom limited oxygen consumption (maximal); minute ventilation, mean pulmonary capillary wedge pressure; and arterial blood gases, pH, and lactate concentrations were measured during treadmill exercise using a slow prot...

GAAR, KERMIT A., JR.,* AUBREY E. TAYLOR, L. JENNINGS OWENS, AND ARTHUR C. GUYTON. Pulmonary capillary pressure and jltration coeficient in the isolated perfused lung. Am. J. Physiol. 213(4): 910-914. 1967.-An “isogravimetric” method was used to estimate the pulmonary capillary pressure, to determine the arterial and venous resistances in the isolated perfused lobe of a dog’s lung, and to determ...

A surface-modified polyethylene glycol-conjugated human hemoglobin (MP4) and alpha alpha-cross-linked human hemoglobin (alpha alpha Hb) were used to restore oxygen carrying capacity in conditions of extreme hemodilution (hematocrit 11%) in the hamster window model preparation. Changes in microvascular function were analyzed in terms of effects on capillary pressure and functional capillary dens...

Subsurface two-phase flow in porous media often takes place in reservoirs with a high ratio between the associated lateral and vertical extent and the lateral and vertical flow time scales. This allows for a two-scale approach with effective quantities for two-dimensional horizontal flow equations obtained from reconstructed hydrostatic vertical pressure and saturation distributions. Here, we d...

There are sex-related differences in venous compliance and capillary filtration in the lower limbs, which to some extent can explain the susceptibility to orthostatic intolerance in young women. With age, venous compliance and capacitance are reduced in men. This study was designed to evaluate age-related changes in venous compliance and capillary filtration in the lower limbs of healthy women....

Modifications which enable simpler operation of the Cunningham-Barth-Kirk microrespirometer are described and an example of its use is quoted. Added advantages include easy positioning of indicator drop in the capillary and thermal equilibration at atmospheric pressure.