chronization therapy. Cardiol Res Pract 2010;22:568918. 32. Porapakkham P, Porapakkham P, Zimmet H, Billah B, Krum H. B-type natriuretic peptide-guided heart failure therapy: a meta-analysis. Arch Intern Med 2010;170: 507–14. 33. Felker GM, Thompson RE, Hare JM, Hruban RH, Clemetson DE, Howard DL et al. Underlying causes and long-term survival in patients with initially unexplained cardiomyopat...

Cardiac resynchronization therapy (CRT) has been shown to improve cardiac function, diminish hospitalization frequency, and enhance quality of life in selected heart failure patients. This benefit is mostly due to improved synchronization of ventricular contraction in the diseased heart. Since heart failure patients represent a heterogeneous group, cardiac resynchronization therapy must be tail...

This report described an 81-year-old woman with severe symptomatic heart failure, reduced ejection fraction, mitral regurgitation, and an electrocardiographic QRS width of 118 ms who had ventricular dyssynchrony identified by echocardiographic tissue synchronization imaging. Because of her severe heart failure symptoms on maximal medical therapy, referral to implant a defibrillator, and mechani...

Background—Numerous criteria believed to define a positive response to cardiac resynchronization therapy have been used in the literature. No study has investigated agreement among these response criteria. We hypothesized that the agreement among the various response criteria would be poor. Methods and Results—A literature search was conducted with the keywords “cardiac resynchronization” and “...