Several new CPR techniques and devices have been developed and tested since the first report of manual closed-chested cardiopulmonary resuscitation (CPR) nearly four decades ago. These devices and techniques include vest CPR, interposed abdominal counterpulation CPR, active compression-decompression CPR, an impedance threshold valve, intra-aortic balloon pump and phased thoracic-abdominal count...

Improvements in techniques in coronary revascularization over the past decade have led to a revival of interest in off-pump coronary artery surgery. A fifth of coronary revascularization procedures are now performed off-pump. Randomized trials comparing off-pump surgery with conventional coronary artery bypass grafting using cardiopulmonary bypass (CPB) mainly included low-risk patients and wer...

Coronary artery bypass grafting (CABG) remains one of the most common procedures worldwide, and remains the gold standard therapy for symptomatic coronary artery disease (CAD) that involves the left main coronary artery, triple vessel CAD with or without left ventricular dysfunction, and other complex coronary CAD not amenable to percutaneous intervention, especially in diabetic patients or tho...

A 54-year-old female with pre-existing idiopathic moyamoya disease developed chest pain with acute myocardial infarction. Coronary angiography detected occluded and stenotic lesions in the coronary arteries. Right coronary artery stenosis was treated by balloon angioplasty and stenting. Because of the restenosis, onpump cardiopulmonary bypass was performed. The operation was uneventful and no p...

Cardiac surgery (CS) with cardiopulmonary bypass (CPB) induces systemic inflammatory response by activating plasma proteins and blood cells. Activated monocytes/macrophages produce inflammatory marker neopterin (NP). The aim was to explore the NP kinetics in first 24 hours after CS according to the CPB use. Significant difference between groups was found for NP levels 12 and 24 hrs after CS, be...

INTRODUCTION The use of coronary artery bypass surgery (CABG) with cardiopulmonary bypass (CPB) or without CPB technique (off-pump) can be associated with different mortality and morbidity and their outcomes remain uncertain. The goal of this study was to evaluate the early outcome of on-pump versus off-pump CABG. METHODS We conducted a retrospective database review of 13866 patients (13560 p...

We aimed to quantify the effect of avoiding cardiopulmonary bypass on outcomes in high-risk patients. Of the 2079 consecutive CABG's performed by three surgeons between April 1997 and September 2002, 389 were classified as high-risk according to the European System for Cardiac Operative Risk Evaluation (EuroSCORE) risk stratification, with a score of >5. The off-pump group had 196 patients and ...

BACKGROUND Antifibrinolytic medications such as ε-aminocaproic acid (EACA) are used in pediatric heart surgery to decrease surgical bleeding and transfusion. Dosing schemes for neonates are often based on adult regimens, or are simply empiric, in part due to the lack of neonatal pharmacokinetic information. The authors sought to determine the pharmacokinetics of EACA in neonates undergoing card...

Left ventricular free wall rupture after myocardial infarction has a high mortality. Suturing techniques of repair may be technically difficult and require cardiopulmonary bypass. We report a case of left ventricular rupture in a 47 year old man managed off pump employing a sutureless technique with Gelatine-Resorcin-Formalin glue and bovine pericardial patches.