Backgrounds Hypotrichosis with juvenile macular dystrophy (HJMD) is a rare genetic disorder caused from mutations in the Cadherin 3 (CDH3) gene. Results In the present study, we reported an Iranian family with three affected members born to a consanguineous parent. Mutational analysis using whole exome sequencing has revealed a nucleotide change in CDH3 gene (NM_001793:exon8:c.830delG) which l...

it’s obvious that road safety is causing large problems and costs in iran with an enormous impact on the well-being of people, economy and productivity. the yearly number of fatalities and injuries is still unchanged. motor vehicle injuries lead the list of injury deaths at the all ages during childhood and adolescence, even in children under 1 yrs of age. understanding the actual of child road...

Hydraulic heritage systems, both underground and exposed, have been known to be sustainable for millennia. Persian and also Roman aqueducts are examples of such hydrosystems. Their values are often overlooked but they have undeniable advantages: they have functional interconnectedness with their surrounding society and ecology, which sometimes leads to revitalization plans. By using the notion ...

a new species of cassiduloid echinoids, pygaulus baghinensis is reported for the first time from aptian sediments of baghin area, west of kerman, iran. the diagnostic features of the species are centrally positioned of the apical disc and approximately low profile of the test. variation in gonopore size in different individuals allows to conclude that p. baghinensis is sexually dimorphic. speci...

Bernanke (2005) hypothesized that a "global savings glut" was causing large trade imbalances. However, we show that the global savings rates did not show a robust upward trend during the relevant period. Moreover, if there had been a global savings glut there should have been a large investment boom in the countries that imported capital. Instead, those countries experienced consumption booms. ...

A new JGP study shows how a disease-causing mutation in RyR2 dramatically alters channel behavior.