We report an unusual case of a 76 year old woman admitted to our hospital for investigation of anemia and palpable epigastric mass. Intraoperatively a huge (19 cm), well defined tumor was found adhering to the stomach wall, protruding into the greater omentum and compressing the transverse colon. A tumorectomy was performed and the greater omentum was removed due to its close relation. Patholog...

Celiac disease (CD) is most probably an immunological disease, precipitated in susceptible individuals by ingestion of wheat gliadin and related proteins from other cereals. The disease shows a strong human HLA association predominantly to the cis or trans encoded HLA-DQ(alpha 1*0501,beta 1*0201) (DQ2) heterodimer. T cell recognition of gliadin presented by this DQ heterodimer may thus be of im...

The outer membrane protein CD of Moraxella catarrhalis is considered to be a potential vaccine antigen against Moraxella infection. We purified the native CD from isolate O35E, administered it to mice, and detected considerable titers of anti-CD antibodies. Anti-CD sera were cross-reactive towards six different M. catarrhalis isolates and promoted bacterial clearance of O35E in a pulmonary chal...

background: celiac disease (cd) is an immune mediated condition that leads to small bowel atrophy that resolves with a gluten free diet (gfd). extra-intestinal manifestations of cd include hypertransaminasemia. in this study, the effects of a gfd on hypertransaminasemia in patients with newly diagnosed cd were studied. methods: ninety eight new diagnosed consecutive patients with cd 40 males an...

introduction: oral lichen planus (olp) is a common mucocutanous disorder with unknown etiology. while current data suggest that oral lichen planus is a cell-mediated autoimmune disease, it might be associated to s+100, cd+4 and cd+8 cells. because of differential diagnosis of olp and oral lichenoid lesion (oll) is usually difficult this study was designed to compare any probable immunohistochem...

Exposure to gluten, a protein present in wheat rye and barley, is the major inducer for human Celiac Disease (CD), chronic autoimmune enteropathy. CD occurs about 1% worldwide population, genetically predisposed individuals bearing leukocyte antigen (HLA) DQ2/DQ8. Gut epithelial cell stress innate immune activation are responsible breaking oral tolerance gliadin, gluten component. To date, only...

Breast carcinoma is one of the most frequently occurring cancers among women with million cases. cancer primary cause death in around world. It major concerns public health due to its high occurrence and growing tendency. This complex functional structure develops from a highly modified apocrine sweat gland female, but remains rudimentary male. embryological into two lines along milk extending ...

Proportional changes of lymphocyte subsets in the peripheral blood were monitored by two-color flow-cytometry in seven leukemia patients who had received allogenic bone marrow transplantation (BMT). Lymphocyte counts, and proportions of T and B-cells returned to normal ranges between the 2nd and 12th months after BMT. Activated T-cells prominently increased after BMT, and the values gradually r...

Myofibroblastoma is a benign tumor composed of spindle cells in clusters and fascicles. To date, only three cases of intracranial myofibroblastoma have been reported. The present study reports the case of a 47-year-old female with meningeal myofibroblastoma. The patient had a history of ovarian cyst resection and presented with paroxysmal mild headaches that had been apparent for 4 years. Magne...

disease). Transplantation is recognized as the most effective form of renal replacement therapy for these patients. Specific disease entities that causing chronic kidney disease are outlined in Box 117.1. Diabetic nephropathy is the most common single disease process leading to renal transplantation. Most renal grafts now function for longer than 10 years. The 1-year survival rate of renal tran...