نتایج جستجو برای: cdh
تعداد نتایج: 919 فیلتر نتایج به سال:
Congenital diaphragmatic hernia (CDH) is a developmental defect of the diaphragm that allows abdominal viscera to herniate into the chest. The reported incidence of CDH is estimated to be between 1 in 2000 to 5000 births. Defects are more common on the left side, with approximately 80% being left sided and 20% right sided. Bilateral CDH defects are rare and have a high incidence of associated a...
Introduction. Vascular endothelial growth factor (VEGF), an angiogenic factor secreted by type II pneumocytes, could play a role in congenital diaphragmatic hernia (CDH) pathogenesis. Animal studies suggest that VEGF accelerates lung growth. Aim. To quantify VEGF on fetal lungs in a nitrofen rat model for CDH and to analyze the effect of tracheal occlusion (TO) in VEGF in fetal lung rats after ...
Congenital Diaphragmatic hernia (CDH) is a condition characterized by a defect in the diaphragm leading to protrusion of abdominal contents into the thoracic cavity interfering with normal development of the lungs. The defect may range from a small aperture in the posterior muscle rim to complete absence of diaphragm. The pathophysiology of CDH is a combination of lung hypoplasia and immaturity...
Congenital diaphragmatic hernia (CDH) is a serious birth defect that accounts for 8% of all major birth anomalies. Approximately 40% of cases occur in association with other anomalies. As sporadic complex CDH likely has a significant impact on reproductive fitness, we hypothesized that de novo variants would account for the etiology in a significant fraction of cases. We performed exome sequenc...
BACKGROUND/AIMS Neuropsychiatric systemic lupus erythematosus (SLE) includes a broad spectrum of neurologic and psychiatric manifestations. One of the most commonly observed neuropsychiatric symptoms is headache. However, the lack of specific clinical distinctions for headache in SLE has made it difficult to elucidate its pathophysiology. The aim of this study is to evaluate the neurometabolic ...
BACKGROUND Congenital diaphragmatic hernia (CDH) is a common birth defect affecting 1 in 3000 births. It is characterised by herniation of abdominal viscera through an incompletely formed diaphragm. Although chromosomal anomalies and mutations in several genes have been implicated, the cause for most patients is unknown. METHODS We used whole exome sequencing in two families with CDH and cong...
In the September 2003 issue of Pediatrics, Stege et al1 discuss the effect of new therapies for congenital diaphragmatic hernia (CDH) on survival. They point out that studies reporting improved survival using high-frequency ventilation, extracorporeal membrane oxygenation, inhaled nitric oxide, and delayed surgery are flawed by selection bias and conclude, after assessing 185 cases of CDH from ...
Congenital diaphragmatic hernia (CDH) can be one of the most clinically challenging neonatal conditions. It occurs in 1 in 2-5000 live births in the UK with no predominance between the sexes. Herniation of abdominal contents into the thorax occurs, however it is the concomitant pulmonary hypoplasia and pulmonary hypertension that can be fatal. CDH was first described as an incidental finding at...
In 1972, Bennett studied the countable dense homogeneous CDH spaces and in 1992, Fitzpatrick, White, and Zhou proved that every CDH space is a T1 space. Afterward Bsoul, Fora, and Tallafha gave another proof for the same result, also they defined the almost CDH spaces and almost T1, T0 spaces, indeed they prove that every ACDH space is an almost T1 space. In this paper we introduce a new type o...
OBJECTIVES To examine operative and perinatal aspects of fetal endoscopic tracheal occlusion (FETO) in congenital diaphragmatic hernia (CDH). METHODS This was a multicenter study of singleton pregnancies with CDH treated by FETO. The entry criteria for FETO were severe CDH on the basis of sonographic evidence of intrathoracic herniation of the liver and low lung area to head circumference rat...
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