BACKGROUND There is an increased prevalence of osteoporosis among patients with celiac disease. However, the relative prevalence of celiac disease among osteoporotic and nonosteoporotic populations is not known, and the benefit of screening the osteoporotic population for celiac disease remains controversial. METHODS We evaluated 840 individuals, 266 with and 574 without osteoporosis, from th...

The clinical spectrum of celiac disease continues to evolve. What was once thought to be a rare disorder affecting young children is now recognized to be very common with a range of symptoms from asymptomatic disease to severely affected persons. Screening for celiac disease has become relatively easily with reliable antibodies against self-antigens (TG) and modified environmental antigens (DGP...

BACKGROUND & AIMS Little is known about the incidence of celiac disease in the general population of children in the United States. We aimed to estimate the cumulative incidence of celiac disease in adolescents born in the Denver metropolitan area. METHODS We collected data on HLA-DR, DQ genotypes of 31,766 infants, born from 1993 through 2004 at St. Joseph's Hospital in Denver, from the Diab...

there are overwhelming reports and descriptions about celiac associated disorders. although there is a clear genetic association between celiac disease (cd) and some gastrointestinal disorders, there are controversial reports claiming an association between cd and helicobacter pylori (h. pylori) infection. different studies indicated the possible association between lymphocytic gastritis and bo...

backgrounds: iron deficiency anemia (ida) is one of the well recognized presentations of celiac disease (cd). according to the lack of data from our population in this regard, we determined the prevalence of cd in patients presenting with ida to see if it is worthwhile to do a precise screening for cd in such patients. methods: this cross-sectional study was conducted on patients referred with ...

background : â  celiac disease (cd) is an immune-mediated inflammation of the small intestine caused by sensitivity to dietary gluten and related proteins in genetically sensitive individuals . recurrent aphthous stomatitis (ras) is an inflammatory condition characterized by painful recurrent, single or multiple ulcerations of the oral mucosa. the association between cd and ras has been evaluat...

celiac disease (cd) is an autoimmune enteropathy induced by the ingestion of gluten in genetically predisposed individuals who carry the hla dq2 or dq8 alleles. the etiology is multifactorial involving genetic and environmental factors, immune response, and intestinal dysbiosis. the innate and acquired t-cell mediated immunity play important roles in the pathogenesis of this disease, particular...

BACKGROUND & AIMS Celiac disease is an increasingly recognized disorder in Caucasian populations of European origin. Little is known about its prevalence in non-Caucasians. Although it is thought to be a cause of iron-deficiency anemia, little is known about the extent to which celiac disease contributes to iron deficiency in Caucasians, and especially non-Caucasians. We analyzed samples collec...

BACKGROUND Celiac disease is present in ~1% of the general population in the United States and Europe. Despite the availability of inexpensive serologic screening tests, ~85% of individuals with celiac disease remain undiagnosed and there is an average delay in diagnosis of symptomatic individuals with celiac disease that ranges from ~5.8-11 years. This delay is often attributed to the use of a...

BACKGROUND/AIMS Migraine headache is one of the most frequent types of headache in children in which multiple factors, including environmental and genetic, are involved. Celiac disease is an autoimmune-mediated disease with intolerance to gluten. The clinical spectrum of celiac disease is wide. Patients may present with malabsorption symptoms or extra-intestinal involvement, or can be totally a...