Hair follicles (HFs) of mammalian epidermis are cycling throughout lifetime in order to continuously generate new hairs. Stem cells (SCs) residing the bulge and hair germ fuel this cycle regeneration that comprises three phases: (a) growth (anagen), where proliferate shaft; (b) HF regression (catagen), keratinocytes undergo apoptosis surviving move upwards regenerate inner bulge; (c) resting (t...

Objective(s): Abnormal lung cell death including autophagy and apoptosis is the central feature in acute lung injury (ALI). To identify the cellular mechanisms and the chronology by which different types of lung cell death are activated during lipopolysaccharide (LPS)-induced ALI, we decided to evaluate autophagy (by LC3-II and autophagosome) and apoptosis (by caspase-3) at different time point...

Increased production and use of nanomaterials has led to an ever growing exposure of livingorganisms to these substances. Limited knowledge about possible toxicity of nanomaterialsand their potential to harm living creatures is becoming a serious concern. To address thisproblem, there is a need for development of diagnostic methods enabling effective determinationof potential toxicity of nanoma...