Abstract Melanoma cells activate Wnt/β-catenin signaling in the tumor microenvironment (TME) to promote progression and suppress dendritic cell-mediated anti-tumor immunity. However, role of β-catenin macrophages its effect on immunity is largely undefined. In this study, using XAV939, a tankyrase inhibitor encapsulated nanoparticles, we explored whether targeting can immunogenicity TME. Our da...
