it is widely thought that bcl-2 family proteins regulate commitment to apoptosis primarily through their capacity to control the permeability of the mitochondrial outer membrane permeabilization (momp) triggers the release of multiple apoptogenic factors into the cytosol and, thereby apoptosis. various bcl-2 family members affect this key event of the apoptotic cascade in different ways, determ...

By means of measurements from cinematograph films of the time taken for human red cells to lose hemoglobin while hemolyzing, it is shown that small concentrations of saponin bring about a relatively small permeability of the cell membrane to the pigment, whereas large concentrations so destroy the membrane that the theoretical time for loss of pigment through a completely permeable membrane (0....

The effect of tris(hydroxymethyl)aminomethane (Tris) buffer on outer membrane permeability was examined in a smooth strain (D280) and in a heptose-deficient lipopolysaccharide strain (F515) of Escherichia coli O8. Tris buffer (pH 8.00) was found to increase outer membrane permeability on the basis of an increased Vo of whole-cell alkaline phosphatase activity and on the basis of sensitivity to ...

application of nanotechnology in medicinal and biological fields has attracted a great interest in the recent yeras. in this paper the cell membrane leakage induced by iron nanoparticles (fe-np) against pc12 cell line which is known as a model of nervous system cell line was investigated by the lactate dehydrogenase (ldh) test. therefore, pc12 cells were incubated with different concentration o...

The low permeability of many wood species causes significant problems during processing. Industrial methods used for increasing reduce strength properties, are energy consuming, and not viable economically. Destruction pit membranes in cell walls can provide an increase without affecting properties. It be accomplished using resonance applied to the membranes. Theoretical analysis calculations h...

A number of antibiotics have been shown to increase markedly the permeability to ions of various cellular membranes and artificial lipid membranes (see, for example, reference 1). I t was, therefore, of interest to test the action of such antibiotics on the single-cell electroplax preparation. Since solutions may be applied separately to the innervated and to the noninnervated membrane, and sin...

The permeability of human red cell membrane to 90 different molecules has been measured. These solutes cover a wide spectrum of nonelectrolytes with varying chemical structure, chain length, lipid solubility, chemical reactive group, ability to form hydrogen bonds, and other properties. In general, the present study suggests that the permeability of red cell membrane to a large solute is determ...

We used computational methods to predict the cell membrane permeability of a medium molecular drug, Bottromycin A2. compared three calculation methods, electronic structure calculation, dynamics (MD) simulation, and empirical method, examined which method was best. As result, we found that first one is best among treated, prediction with high accuracy can be expected by increasing number experi...

Photocatalytic membranes exhibit great potential for water treatment since they combine the filtration and photo degradation in a single unit. Although blending photocatalytic nanoparticles into polymeric thin film remains the simplest method to prepare the photocatalytic membrane, the entrapped photocatalyst showed less catalytic activity due to the agglomeration and shielding effects in the p...

Spherocytosis is a genetic disease characterized by specific morphological changes in erythrocytes. Their fragility causes them to lyse when passing through microcapillaries. The changing shape and breaking of erythrocytes can be evaluated by the transmittance of a cell suspension. Transmittance as a function of time for cells under osmotic stress can be used to retrieve parameters possibly rel...