نتایج جستجو برای: cellular reprogramming

تعداد نتایج: 449138  

Journal: :European Journal of Heart Failure 2016

Journal: :International Journal of Molecular Sciences 2017

Journal: :Cell 2012
Yosef Buganim Dina A. Faddah Albert W. Cheng Elena Itskovich Styliani Markoulaki Kibibi Ganz Sandy L. Klemm Alexander van Oudenaarden Rudolf Jaenisch

During cellular reprogramming, only a small fraction of cells become induced pluripotent stem cells (iPSCs). Previous analyses of gene expression during reprogramming were based on populations of cells, impeding single-cell level identification of reprogramming events. We utilized two gene expression technologies to profile 48 genes in single cells at various stages during the reprogramming pro...

Journal: :Cell stem cell 2015
Daniel H Kim Georgi K Marinov Shirley Pepke Zakary S Singer Peng He Brian Williams Gary P Schroth Michael B Elowitz Barbara J Wold

Cellular reprogramming highlights the epigenetic plasticity of the somatic cell state. Long noncoding RNAs (lncRNAs) have emerging roles in epigenetic regulation, but their potential functions in reprogramming cell fate have been largely unexplored. We used single-cell RNA sequencing to characterize the expression patterns of over 16,000 genes, including 437 lncRNAs, during defined stages of re...

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