Introduction: In cemented total hip arthroplasty, the implant needs a mechanically stable cement-bone interface for its survival. This can be achieved by adequate cement penetration into the bone lacunar and trabecular spaces. Many studies have been conducted to investigate the strength of the cement-bone interface in relation to the amount of cement penetration, but mainly on a macro-scale [1]...

BACKGROUND The aim of this study is to evaluate the effect of self-invented compound calcium phosphate cement upon the proliferation and osteogenesis of bone mesenchymal stem cells (BMSCs). METHODS Four groups including traditional calcium phosphate cement, modified calcium phosphate cement, modified calcium phosphate cement plus bone morphogenetic protein (BMP), and control groups were estab...

Many bioactive bone cements were developed for total hip replacement and found to bond with bone directly. However, the mechanical properties at the bone/bone cement interface under load bearing are not fully understood. In this study, a bioactive bone cement, which consists of strontium-containing hydroxyapatite (Sr-HA) powder and bisphenol-alpha-glycidyl dimethacrylate (Bis-GMA)-based resin, ...

BACKGROUND The integrity of bone-cement interface is very important for the stabilization and long-term sustain of cemented prosthesis. Variations in the bone-cement interface morphology may affect the mechanical response of the shape-closed interlock. METHODS Self-developed new reamer was used to process fresh pig reamed femoral canal, creating cortical grooves in the canal wall of experimen...

The attachment of an implant material to bone relates to surface roughness and surface chemistry. There is a relatively low chemical bonding strength of so-called bioactive surfaces. Hydroxyapatite interfaces typically have an interfacial tensile strength of 0.15-1.5 MPa. An attachment force similar to that of bioactive surfaces might also be reached through mechanical interlock with ordinary b...

Gelation and densification of calcium-silicate-hydrate take place during cement hydration. Both processes are crucial for the development of cement strength, and for the long-term evolution of concrete structures. However, the physicochemical environment evolves during cement formation, making it difficult to disentangle what factors are crucial for the mechanical properties. Here we use Monte ...

The study measured haematological and cytogentic parameters in workers occupationally exposed to cement dust in order to test the hypothesis that cement dust exposure may perturb these functions. Assessments of haematological, and cytogentic were performed in 30 workers occupationally exposed to cement dust and 30 matched unexposed controls. The RBC level has no significant change and WBC level...

Patients with pathologic hip fractures or impending pathologic proximal femur fractures are at a high risk for developing bone cement implantation syndrome during cemented femoral arthroplasty. Comorbid conditions of patients who sustain these fractures, including cardiopulmonary compromise and permeable, highly vascular bone related to metastatic disease, put them at risk for sudden death. Red...

OBJECTIVES This cross-sectional study aimed to determine the effects of exposure to cement dust on Fractional Exhaled Nitric Oxide (FeNO) in non-smoking cement mill workers. SUBJECTS AND METHODS We recruited 121 apparently healthy male volunteers, 90 of them were non-smoking cement mill workers and 31 non-smoking un-exposed subjects served as control. The mean age of cement mill workers was 3...

BACKGROUND Improvements to enforce primary fixation in cemented total knee arthroplasty have been suggested to be a key issue for long-term survival. In this context, it has been questioned whether specific implant design features influence bone cement morphology and hence primary interface strength. The purpose of this study was to investigate in vitro the influence of cement pockets on the ti...