OBJECTIVES To determine the effect of central corneal thickness (CCT) on the measurement of intraocular pressure (IOP) and on the resultant reclassification of patients as having primary open-angle glaucoma (POAG), normal tension glaucoma (NTG), or ocular hypertension (OHT). METHODS Intraocular pressure (Goldmann applanation tonomety) and CCT (ultrasound pachymetry) were measured in 22 patien...

PURPOSE To investigate the association between corneal pachymetry and visual field progression in patients with chronic open-angle glaucoma. DESIGN Retrospective case-control study. PARTICIPANTS Eighty-eight patients with primary open-angle glaucoma, pseudoexfoliative glaucoma, pigmentary glaucoma, or normal-tension glaucoma, followed for an average of 8 years, who had visual field loss and...

PURPOSE To examine the relationship between corneal biomechanical properties and retinal vascular caliber in Singaporean children in a cross-sectional study of 257 healthy subjects from the Singapore Cohort Study of Risk Factors for Myopia. METHODS Corneal hysteresis (CH), corneal resistance factor (CRF), central corneal thickness (CCT), and corneal compensated intraocular pressure (IOP(CC)) ...

PURPOSE To examine the relationship of diabetes and hyperglycemia with central corneal thickness (CCT) in Malay adults in Singapore. DESIGN Population-based cross-sectional study. PARTICIPANTS Three thousand two hundred eighty Malay adults ages 40-80 years living in Singapore. METHODS The study population was selected using an age-stratified random sampling procedure of Malay 40- to 80-ye...

purpose : to evaluate central corneal thickness (cct) in patients with juvenile glaucoma and compare it with that of normal individuals methods : a prospective, case-control study was performed on 80 eyes with juvenile glaucoma who attended glaucoma clinic in farabi eye hospital, tehran, iran and 107 clinically normal healthy eyes. standard automated perimetry (sap) was performed for all the pa...

PURPOSE Studies have suggested that corneal biomechanical properties influence intraocular pressure (IOP) measurements, namely central corneal thickness (CCT) and corneal hysteresis (CH). The present study aimed to investigate the associations of CH and CCT with glaucoma development. METHODS We performed a review of the literature and meta-analysis of observational studies (2006-2016) that in...

PURPOSE To examine if central corneal thickness (CCT) is different in emmetropia and high myopia. METHODS 57 emmetropic subjects (0 to + 1.5 D) and 48 high myopes (all more than - 6 D in spherical equivalent refraction) were studied. CCT was measured by a Haag-Streit Optical Low-Coherence Reflectometry (OLCR) pachymeter, a recently developed high precision pachymeter with a standard deviation...

Background: The optic nerve damage with the ultimate loss of vision resulting from a clutch diseases named Glaucoma. In many conditions including, corneal dystrophies, edema, and endothelial cornea, important biometric is Central thickness (CCT). Objective: To find difference in mean CCT spectral-domain optical coherence tomography ultrasound pachymetry patients presenting Material & Method...

AIMS The tonographic effect is a phenomenon of intraocular pressure (IOP) reduction following repeated tonometry. This study examines whether the tonographic effect occurs following IOP measurement performed with Ocular Response Analyzer (ORA). METHODS Both eyes of 31 glaucoma patients and 35 healthy controls underwent nine IOP-measurements performed with GAT and ORA. The number of GAT and OR...

Purpose To evaluate the ability of a targeted genome-wide association study (GWAS) to identify genes associated with central corneal thickness (CCT). Methods A targeted GWAS was used to investigate whether ten candidate genes with known roles in corneal development were associated with CCT in two Singaporean populations. The single nucleotide polymorphisms (SNPs) within a 500 kb interval enco...