Sleep-disordered breathing (SDB) is highly prevalent in patients with spinal cord injury (SCI); the exact mechanism(s) or the predictors of disease are unknown. We hypothesized that patients with cervical SCI (C-SCI) are more susceptible to central apnea than patients with thoracic SCI (T-SCI) or able-bodied controls. Sixteen patients with chronic SCI, level T6 or above (8 C-SCI, 8 T-SCI; age 4...

By definition, growth factors are polypeptides that modulate the proliferation of mammalian cells by acting on their receptors at low concentration. Based on similarities in their sequences and their receptors, growth factors can be divided into several superfamilies including platelet-derived growth factors, epidermal growth factors, insulin-like growth factors, the transforming growth factor-...

Approved: ____________________________________ Thesis Supervisor ____________________________________ Title and Department ____________________________________ Date COMPLEMENT FACTOR H REGULATION IN THE CENTRAL NERVOUS SYSTEM by Laura Anne Fraczek A thesis submitted in partial fulfillment of the requirements for the Doctor of Philosophy degree in Immunology in the Graduate College of The Univer...

Consistent chromosomal rearrangements are found in a large number of hematopoietic tumors. In many cases, these rearrangements disrupt genes whose normal function is required for the proper development of blood cells. Excellent examples are the chromosomal rearrangements t(8;21)(q22;q22), t(12;21)(p13;q22), and inv(16)(p13q22) that disrupt two of the genes encoding a small family of heterodimer...

The paper examines the development of foreign trade institutions and policies in Central European countries that were invited to negotiate accession to the EU. The dismantling of state trading has dramatically liberalized conditions in market access. Yet, with the exception of Estonia and to a lesser extent the Czech Republic, they have followed the policy of bilateral rather than multilateral ...

Central auditory processing disorders among school-age children have been challenging to identify and treat. Many issues remain that need to be resolved. Here, we compare and contrast findings on 331 school-age children who were given two of the more common central auditory processing disorder tests (Staggered Spondaic Word [SSW] Test and the SCAN Screening Test for Auditory Processing Disorder...

The identification of risk factors for ovarian cancer is crucial in prevention of the disease. This pathology is the leading cause of death from gynecological malignancies. The aim of this study was to evaluate the role of factors influencing hormonal levels such as body mass index (BMI), BMI at age 20, waist-to-hip ratio (WHR), oral contraceptive (OC) use, and risk of ovarian cancer. A case-co...