We have developed and employed a stereotaxic coordinate system for the pig brain based on eternal skull landmarks. Sagittal, coronal, and horizontal planes were defined. Based on histological maps and ventricular casts, the coordinates for locating the lateral ventricles were described. Guide tubes leading to the lateral ventricles have been chronically implanted. This access route to the ventr...

Brain development during late childhood and adolescence is characterized by decreases in gray matter (GM) and increases in white matter (WM) and ventricular volume. The dynamic nature of development across different structures is, however, not well understood, and the present magnetic resonance imaging study took advantage of a whole-brain segmentation approach to describe the developmental tra...

Anatomically corrected malposition of great arteries (ACMGA) is a rare form of congenital heart disease in which the great arteries arise above the anatomically correct ventricles but have abnormal spatial relationship. We report the case of a 26-year-old female with ACMGA and tunnel type of subaortic obstruction. The abnormal relationship and segmental arrangement necessitates systematic appro...

Kerber, C., and Blank, E. (1974). Archives of Disease in Childhood, 49, 560. Total brain opacification in children during angiography. Total brain opacification is an angiographic method of neuroradiological examination in children which will often make examination with air unnecessary. The substance of the brain becomes temporarily opaque while the ventricles and avascular masses are radioluce...

Inflammatory disorders of the central nervous system such as multiple sclerosis and acute disseminated encephalomyelitis involve an invasion of immune cells that ultimately leads to white matter demyelination, neurodegeneration and development of neurological symptoms. A clinical diagnosis is often made when neurodegenerative processes are already ongoing. In an attempt to seek early indicators...

The three-dimensional dynamics and morphology of the human embryonic brain have not been previously analyzed using modern imaging techniques. The morphogenesis of the cerebral vesicles and ventricles was analyzed using images derived from human embryo specimens from the Kyoto Collection, which were acquired with a magnetic resonance microscope equipped with a 2.35-T superconducting magnet. A to...