Brachial plexus root avulsion (BPRA) leads to dramatic motoneuron death and glial reactions in the corresponding spinal segments at the late stage of injury. To protect spinal motoneurons, assessment of the affected spinal segments should be done at an earlier stage of the injury. In this study, we employed 18F-FDG small-animal PET/CT to assess the severity of BPRA-induced cervical spinal cord ...

The human circadian timing system regulates the temporal organization of several endocrine functions, including the production of melatonin (via a neural pathway that includes the spinal cord), TSH, and cortisol. In traumatic spinal cord injury, afferent and efferent circuits that influence the basal production of these hormones may be disrupted. We studied five subjects with chronic spinal cor...

INTRODUCTION Delayed post-traumatic spinal cord infarction is a devastating complication described in children. In adults, spinal cord ischemia after cardiovascular interventions, scoliosis correction, or profound hypotension has been reported in the literature. However, delayed spinal cord infarction after minor head trauma has not been described yet. CASE PRESENTATION We report the case of ...

Impaired respiratory function is a common and devastating consequence of cervical spinal cord injury. Accordingly, the development safe effective treatments to restore breathing critical. Acute intermittent hypoxia has emerged as promising therapeutic strategy treat insufficiency in individuals with Since original report by Bach Mitchell (1996) concerning long-term facilitation phrenic motor ou...

BACKGROUND There are few reports regarding surgical management of multilevel cervical spinal stenosis with spinal cord injury. Our purpose is to evaluate the safety and feasibility of open-door expansive laminoplasty in combination with transpedicular screw fixation for the treatment of multilevel cervical spinal stenosis and spinal cord injury in the trauma population. METHODS This was a ret...

BACKGROUND Traumatic spinal cord injury remains a serious public health and social problem. Although incidence rates are decreasing in our environment, it is a high cost condition that is associated with great disability. The objective of this study was to describe the epidemiological and demographic characteristics of traumatic spinal cord injury and to analyse its epidemiological changes. M...

The hypermobility of the pediatric bony cervical spine allows deformation of the musculoskeletal structures beyond physiologic extremes, permitting direct trauma or ischemic injury of the spinal cord followed by spontaneous reduction of the bony spine. This predisposes to a spinal cord injury without radiological abnormality (SCIWORA) [1] . SCIWORA has positive neurologic Received: August 5, 20...

Central cord syndrome is the most common type of incomplete spinal cord injury. This syndrome most often occurs in older persons with underlying cervical spondylosis caused by a hyperextension mechanism. It also occurs in younger persons who sustain trauma to the cervical spine and, less commonly, as a result of nontraumatic causes. The upper extremities are more affected than the lower extremi...

objective: it has been suggested that the vascular endothelial growth factor (vegf) gene expression plays an important role in radiation-induced injury to the spinal cord. this study assesses the radioprotective effects of n-acetyl-5-methoxytryptamine (melatonin) through its modulation of vegf expression after localized irradiation of the cervical spinal cord. materials and methods: in this exp...