One of the hardest tasks for a physician is to treat and take care of patients suffering from such chronic disease as diabetes. The difficulties arise mainly because the medical treatment and the necessary follow up demand that the physician interfere with, or at least influence, the whole lifestyle of the patient. The diabetic must pursue a distinct way of daily living: he must change his eati...

Editorial When we look back on the past 15-year history of cartilage repair, it is clear that remarkable progress has been made in this area. There is no doubt that a lot of studies have been carried out on cartilage repair and chondrocytes since Brittebergs' report on ACI in 1994 [1]. I would like to introduce our multi-pronged approach to cartilage repair. After the 1994 report [1], we perfor...

The role of hormones as sensitizers in mammary carcinogenesis can be surmised on a priori grounds: (a) from general evidence of hormone involvement in the maturation of mammary tissue; (b) from differences in incidence of mammary tumors between the sexes; (c) from dietary influences on the incidence of mammary tumors, a high-fat diet affecting the hormonal status of the body (8); and (d) more s...

Mutagenesis is a well-known benchmark machine learning dataset. In this paper we present an overview of results for various methods applied to this dataset. In particular, we present a new result based on an ensemble method using Aleph-generated theories in which we achieve a cross-validated accuracy of 95.8%. This is the highest predictive accuracy to date, and we believe begs the question “Is...

this study was conducted to evaluate the effect of ginger powder on the performance of salmonella challenged broiler chicks and to compare its efficacy as growth promoter with an antibiotic, avilamycin. in a completely randomized design, 300 chicks were divided into six groups, five replicates with 10 birds per each replicate. the treatments included negative control (basal diet without ginger ...

Pacemaker/implantable cardioverter-defibrillator (ICD) lead endocarditis remains a challenging diagnosis in cardiology. Several parameters can be involved in the clinical path leading to the definite diagnosis. Clinical appearance and physical findings, together with transoesophageal echocardiography and serum levels of inflammatory parameters, are necessary in the workup towards the diagnosis....

A keynote presentation at the 2012 Computer Applications in Archaeology (CAA) conference in Southampton (UK) proposed the use of grand challenges as a vehicle for identifying and pursuing major advances in Digital Archaeology. At the same time, it was argued that this should be a collaborative venture. This was taken forward at a round table session at the 2014 CAA in Paris, and a number of pap...

Milton Charles Winternitz received his B.A. degree from the Johns Hopkins University at the age of eighteen years and thereupon entered the Johns Hopkins University School of Medicine. At this early age he began what was to be a brilliant career as a student of medicine, teacher, administrator , scientist, humanitarian, and philosopher. Rarely is one individual endowed with outstanding proficie...

Structural realist interpretations of generally relativistic spacetimes have recently come to enjoy a remarkable degree of popularity among philosophers. I present a challenge to these structuralist interpretations that arises from considering cosmological models in general relativity. As a consequence of their high degree of spacetime symmetry, these models resist a structuralist interpretatio...