Introduction Sexually transmitted diseases are not only highly prevalent in many populations of the developing world, but exhibit some special features. These include a high rate of complications and sequelae as a result of delayed or inadequate treatment, the important problem of antimicrobial resistance, particularly in Neisseria gonorrhoeae and Haemophilus ducreyi, and a high frequency of ge...

Identification of antigenically conserved surface components of Haemophilus ducreyi may facilitate the development of reagents to diagnose and prevent chancroid. A hybridoma derived from a mouse immunized with nontypeable Haemophilus influenzae produced a monoclonal antibody (MAb), designated 3B9, that bound to 35 of 35 H. ducreyi strains isolated from diverse geographic regions. The MAb 3B9 bo...

OBJECTIVES Male circumcision is associated with reduced risk of HIV infection. This may be partly because of a protective effect of circumcision on other sexually transmitted infections (STI), especially those causing genital ulcers, but evidence for such protection is unclear. Our objective was to conduct a systematic review and meta-analyses of the associations between male circumcision and i...

Using catalase as a source of heme, we have developed both clear plate and broth media for the growth of Haemophilus ducreyi, the causative agent of chancroid. In the broth medium, the growth phase of the organism can be monitored and the organisms achieve a cell density of > 10(8) CFU/ml.

. Epidemiology . Latest data from GUM clinics reports in England [HPA 2013] . Chancroid is disappearing even from countries where Haemophilus ducreyi was once endemic. In some areas it may have disappeared already. Herpes simplex virus type 2 (HSV-2) is now the most common cause of genital ulceration in all countries. . Management: There have been no recent developments in the field of management.