background and objective: approximately half of patients with diffuse large b-cell lymphoma are cured with current chemotherapy regimens. the purpose of this study was to evaluate bax and bcl2 expression and their relationship with the response to chemotherapy. materials and methods this study was a prospective analysis on 44 patients with diffuse large b-cell lymphoma. their specimens were sta...

the effects of combined radiotherapy (rt) and chemotherapy in the severity of cytogenetic alterations expressed as micronucleus (mn) in peripheral blood lymphocytes of patients treated for esophageal cancer was evaluated. to do this, blood was obtained from 23 and 15 esophageal cancer patients scheduled for chemo-radiotherapy and rt alone, respectively, before, during, and after treatment. bloo...

abnormalities of the thyroid gland are among the most frequent endocrine complications observed in childhood cancer survivors. we report an 11 years old girl who developed central hypothyroidism and acth deficiency during the chemotherapy for cns relapse of acute lymphoblastic leukemia before receiving radiotherapy. keywords: thyroid gland, hypothyroidism, chemotherapy, acute lymphoblastic leuk...

background: chemotherapy-induced amenorrhea is one of long term side effects of adjuvant chemotherapy in patients with breast cancer which may interfere with their future reproductive function. although amenorrhea is well recognized, the actual incidence following taxanes remains uncertain. methods: in a cross sectional study, we identified breast cancer patients aged 45 years or younger who we...

the male breast cancer (mbc) is a very rare neoplasm which accounts for 0.5-1% of the total cases of breast cancer. bilateral involvement is reported to occur in fewer than 2% of all the diagnosed cases of mbc, and synchronous tumors are very rare. because of its rarity, little is known about mbc etiology, its clinical findings and treatment. most patients present with a painless breast mass. t...

rhabdomyosarcomas are the most common soft tissue sarcoma in adult and children that accompany with skeletal muscle differentiation. skin metastasis of rhabdomyosarcomas is unusual and has only been sporadically reported in literature. in this paper we present a case of skin metastasis of rhabdomyosarcoma in an 8-year-old girl that has treated with chemotherapy.

twenty-one patients with advanced breast cancer (7 premenopausal and 14 postmenopausal women) were treated with a combination of cyclophosphamide, doxorubicin, and cisplatin (cap). the median age of the patients was 43 years (range 36-61). this therapy was repeated every 3 weeks. nine patients (group 1) received cap as primary therapy for metastatic breast cancer, and twelve patients (group 2) ...

conclusions: according to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy-induced nausea and vomiting. however, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy. results: findings of the study indicated that subjects receiving ginger showed significant redu...

Background: The rate of recurrence and mortality in high-risk prostate cancer remains high. On the other hand, the use of chemotherapy in metastatic prostate cancer has improved overall survival of patients. The aim of this study was to evaluate the effect of neoadjuvant chemotherapy alone on increasing survival of patients with high risk localized prostate cancer Methods: This is a systematic...