The phenomenon of chirality, common in nature, pertains also to food components. The effect of the chiral structure of chemical compounds is the occurrence of optical isomers, i.e. enantiomers. The only source of optically active substances are living organisms, which produce most frequently mostly one of isomers. Proteins and carbohydrates are chiral: amino acids are found in proteins only in ...

Tandem reactions and consecutive catalysis (or relay catalysis) have been receiving considerable attention in organic synthesis due to their abilities of constructing multiple new chemical bonds to build complex chiral molecules in a single operation. Transition-metal-catalyzed asymmetric hydrogenation is one of the most widely used and reliable catalytic methods for preparation of chiral molec...

The driving force of homoand heterochiral complex formation in mixtures of chiral compounds is, probably, the effort of the system to separate the most symmetric associates from the less symmetric ones. A possible way to achieve separation of these associates is distribution between two phases. Therefore, during the separation of (a certain part) diastereoisomers similar trends can be observed ...

In recent years there has been considerable interest in the synthesis and separation of enantiomers of organic compounds especially because of their importance in the biochemistry and pharmaceutical industry. Frequently the methods used for the separations, for monitoring the progress of an asymmetric synthesis or optical purity of the products are chromatographic with either liquids, gases, or...

Unprecedented two homochiral Cd(ii) enantiomers [Cd(dtba)(bpp)]n (1: 1P and 1M) (H2dtba = 2,2'-dithiodibenzoic acid, bpp = 1,3-bis(4-pyridyl)propane), were obtained by self-assembly with mixed achiral flexible ligands. Single-crystal X-ray diffraction analysis reveals that complexes 1P and 1M crystallize in trigonal space groups P3121 and P3221, respectively. The compounds are optically active,...

This review describes current analytical technology for the analysis of chiral constituents in essential oils and other natural volatiles, flavor and fragrance compounds, and covers some important results achieved by natural compound chemists, food chemists, perfumers, and molecular biologists. The technique of enantioselective gas chromatography (GC) is described and applied for assigning abso...

Copyright: © 2014 Maher HM. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Chiral molecules are constituents of a large proportion of therapeutic agents. Chiral compounds exist in two enantiomeric forms, whic...

Naringenin and eriodictyol are chiral flavanones widely present in citrus fruits and herbal products. Pharmacological interest in the two flavanones is well known. Due to the chiral carbon atom, the compounds always exist in the racemic form. The present study reported a stereospecific HPLC method for the enantioseparation of naringenin and eriodictyol, which was performed on an amylase-based c...

Enantioenriched secondary alcohols represent an important class of molecules found in numerous intermediates, chiral building blocks, and biologically active compounds. Asymmetric reduction of prochiral ketones constitutes the most straightforward way to form these important moieties. Traditionally, stoichiometric amounts of chiral ligands were used together with an aluminium or a boron hydride...

Chiral segregation of enantiomers or chiral conformers of achiral molecules during self-assembly in well-ordered crystalline superstructures has fascinated chemists since Pasteur. Here we report spontaneous mirror-symmetry breaking in cubic phases formed by achiral multichain-terminated diphenyl-2,2'-bithiophenes. It was found that stochastic symmetry breaking is a general phenomenon observed i...