The serologic and clinical manifestation of infection with Mycoplasma pneumoniae were studied in children during the three years from October 1979 to December 1981. Pneumonia was diagnosed in 107 of the 430 patients with lower respiratory tract infections; mycoplasma pneumonia was diagnosed in 52 of these 107 (20 males and 32 females aged one to 14 years). See Fig. 1. By single serology, seropo...

BACKGROUND The role of cytokines in the pathogenesis of pneumonia is still poorly understood. In a previous study the diagnostic value of measuring blood concentrations of interleukin 6 and interferon gamma was established. In the present study the value of blood concentrations of interleukin 8, granulocyte-colony stimulating factor, and lactoferrin as markers of bacteraemic pneumonia is evalua...

Activation of complement represents one means of natural resistance to infection from a wide variety of potential pathogens. Recently, properdin, a positive regulator of the alternative pathway of complement, has been shown to bind to surfaces and promote complement activation. Here we studied whether properdin-mediated complement activation occurs on the surface of Chlamydia pneumoniae, an obl...

The in vitro and in vivo activities of azithromycin against chlamydia were investigated. The MIC of azithromycin for five standard strains of different species of chlamydia and six wild-type strains of Chlamydia pneumoniae was 0.125 microgram/ml, which was superior to that of erythromycin but inferior to those of clarithromycin and minocycline. However, the therapeutic effect of a 7-day course ...

BACKGROUND Evidences support the possible involvement of microorganisms such as Chlamydia pneumonia in the pathogenesis of ischemic heart diseases through a chronic inflammatory process. The aim of this study was to determine the relation between Chlamydia pneumoniae seropositivity with acute myocardial infarction and its related risk factors. METHODS In this case-control study, 88 patients a...

Chlamydiae are obligate intracellular pathogens that replicate within a membrane-bound compartment (the inclusion) and are associated with important human diseases, such as trachoma, pneumonia, and atherosclerosis. We have examined the interaction of the host autophagic pathway with Chlamydia trachomatis serovar L2 by using the specific autophagosomal stain monodansylcadaverine, antibodies to a...

Various microorganisms such as Streptococcus pneumonia, Haemophilus influenza, Chlamydia spp, and Mycoplasma pneumonia can cause ARI. The ginger flower which contains various phytochemicals that have potential anti-microbial. Recent study was aimed to explore the anti-microbial properties of extract. This experimental in vitro with disc diffusion method. ethanol extract Ginger flowers obtained ...

Bacteria of the genus Chlamydia belong to order Chlamydiales, within family Chlamydiaceae. These intracellular parasites have a different biphasic reproductive cycle than other bacteria. The important Chlamydiaceae are trachomatis, Chlamydophila pneumoniae and psittaci. trachomatis Clamydophila primary human pathogens. is transmitted by sexual contact. It causative agent LGV (lymphogranuloma ve...

INTRODUCTION Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases. Serotypes of C. trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern. Serotype A, a trachoma-associated strain, is known for its limited disseminatio...

Abstract The clinical characteristics and diagnosis of ten cases with severe Chlamydia psittaci pneumonia were analyzed. Ten patients had high fever, cough, or diarrhea, all a history contact birds poultry. white blood cell count the was normal slightly increased. percentage neutrophils ( N %) C reactive protein significantly Chest computer tomography showed patchy consolidation both lungs, one...