TO THE EDITOR—Brucellosis is a common zoonotic disease worldwide [1]. The epidemiology of human brucellosis has drastically changed owing to changing sanitary and socioeconomic conditions, and the substantial increase in international travel. New foci of human brucellosis have emerged or reemerged, with brucellosis becoming a travel-related disease, particularly in nonendemic areas [2–4]. Aware...

Infectious Common HIV/AIDS Typhoid fever Babesiosis Malaria Uncommon Viral hepatitis Tuberculosis Histoplasmosis Brucellosis Noninfectious Common Sarcoidosis Chronic corticosteroid use Antilymphocyte globulin Cancer chemotherapy Radiation therapy Rheumatoid arthritis Systemic lupus erythematosus Hodgkin’s disease Chronic alcohol abuse Uncommon CD4 lymphocytopenia Severe combined immunodeficienc...

Brucellosis is the most widespread zoonosis in the world. The disease is endemic in countries bordering the Mediterranean [1–3]. It is a multisystem disease that may present with a broad spectrum of clinical manifestations and complications. Neurologic manifestations of brucellosis are rare, occurring in 3%–5% of patients with systemic brucellosis [4]. Nervous system manifestations are very het...

Brucellosis is a chronic granulomatous infection caused by intracellular Gram-negative bacteria belonging to Brucella species. While uncommon in the United States, northern Europe and Eastern Asia, it is common in the Middle East, southern Europe, and South America [1]. Human brucellosis is a potentially life-threatening multisystem disease which requires combined and prolonged treatment with a...

Brucellosis is an important zoonosis and a significant cause of reproductive losses in animals. Abortion, placentitis, epididymitis, and orchitis are the most common clinical manifestations in animals. In humans, brucellosis is a debilitating and chronic disease, which may affect a variety of organs. Clinical diagnosis of brucellosis is not easily achieved. Laboratory testing is therefore very ...

Brucella sp. antibodies, despite falling to low levels, can remain measurable after recovery from acute brucellosis (1). Recently, several studies have shown the persistence of Brucella sp. DNA in both chronic brucellosis patients and asymptomatic subjects with a history of brucellosis (2–4, 6). However, to our knowledge, the association between serum antibodies and Brucella sp. DNA has not bee...

Background: Brucellosis is the major bacterial zoonoses of global importance caused by Brucella spps. FCγRIIA receptor plays a central role in phagocytosis of IgG2-opsonized bacteria. FCγRIIA exhibits allelic polymorphisms with different capacities for binding IgG2 and phagocytosis. Cells expressing Fc γ RIIa-H131, bind more efficiently to complexes of IgG2 than those expressi...

* Corresponding author at: Ayse Albayrak, Department of Clinical Bacteriology and Infectious Diseases, Erzurum Region Education and Research Hospital, Erzurum, Turkey. Tel: +90-44223255 61, Fax: + 90-4422325090. E-mail address: [email protected] Brucellosis, a bacterial disease caused by members of the genus Brucella, remains one of the most common zoonotic diseases worldwide (1-3). The...