Rheumatoid arthritis is a chronic inflammatory disorder that affects mainly synovial joints. The disease is responsible for the destruction of articular cartilage and ankylosis of the joints. Classified as an autoimmune disorder, rheumatoid arthritis can also cause inflammation in other organs such as the blood vessels, skin and lungs. Symptoms of rheumatoid arthritis include joint pain and sti...

introduction: rosemary, rosmarinus (r.) officinalis l. is a well-known plant with several useful properties such as analgesic, anti-inflammatory and anti-neurodegenerative. it has been used in folk medicine to alleviate rheumatic pain, stomachache and dysmenorrhea. rosemary has several constituents such as rosmarinic acid which can be responsible for therapeutic properties been noted with rosem...

Background: Acne vulgaris is a chronic and self-limiting inflammation disorder of the pilosebaceous unit, generally manifested in adolescents with polymorphic lesions, such as comedones, papules, nodules, cyst. Brain-derived neurotrophic factor (BDNF) member neurotrophins that can be downregulated because stress. It suspected lower BDNF level induced inflammatory process, although its relations...

Chronic obstructive pulmonary disease (COPD) is a systemic inflammatory disorder. It often causes weight loss, which considered poor prognostic factor. A Japanese herbal Kampo medicine, Hochuekkito (TJ-41), has been reported to prevent inflammation and loss in COPD patients, but the underlying biological mechanisms remain unknown. In present study, we investigated role of TJ-41 vivo using mouse...

Autoimmune pancreatitis is a recently described chronic inflammatory disease of the pancreas which appears to be part of a systemic disorder characterized by a lymphoplasmacytic infiltrate in affected organs that is rich in IgG4 positive cells. The inflammatory component of the disease appears to resolve with steroid treatment, though relapses do occur. Here we briefly discuss the role of stero...

Historically, AA amyloidosis accounts for almost half of the deaths among patients with juvenile chronic arthritis, mainly due to complications of end stage renal failure. Improved survival has been reported in patients whose underlying inflammatory disorder was brought to remission. Tumour necrosis factor (TNFα) blocking agents have been used successfully in the treatment of inflammatory disor...

Historically, AA amyloidosis accounts for almost half of the deaths among patients with juvenile chronic arthritis, mainly due to complications of end stage renal failure. Improved survival has been reported in patients whose underlying inflammatory disorder was brought to remission. Tumour necrosis factor (TNFα) blocking agents have been used successfully in the treatment of inflammatory disor...

Kimura disease is a rare idiopathic chronic inflammatory disorder. It typically presents in the head and neck area, whereas bilateral involvement is unusual. Its diagnosis requires it to be differentiated from other inflammatory diseases and from head and neck tumors. Treatment methods include conservative management, steroid administration, radiotherapy, and surgery; however, no single treatme...

Ankylosing spondylitis (AS) is a chronic systemic inflammatory disorder. It primarily affects the axial skeleton through involvement of the peripheral joint scan occurs. Temporomandibular joint (TMJ) involvement in AS varies from 4% to 35%. Here, we present a case of a 35-year-old male, follow-up of AS from last 8 years on nonsteroidal anti-inflammatory drugs, presented with fresh complaints of...

The syndrome of acute inflammatory idiopathic polyneuropathy is well known, the predominently motor type of which is recognised by the name of Guillain-Barre Syndrome (GBS), in which the maximum neurological deficit develops rapidly in days, plateaus for weeks and then subsides with the recovery occurring in weeks to months. Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) has e...