240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

240 Mold Sensitization in Chronic Rhinosinusitis Patients Radoslaw Gawlik, MD, PhD, and Eugeniusz Czecior, MD, PhD. Internal Medicine, Allergy and Clin Immunology, Silesian University of Medicine, Katowice, Poland; Silesian University of Medicine, Zabrze, Poland. Background: It is estimated that about 10% of the population have IgE antibodies to common inhalant molds. Exposure to fungal allerge...

Invasive fungal infections have become a major cause of mortality in immunocompromised individuals. Despite the current availability of number of highly active antifungal agents, overall mortality remains around 40%. Importantly, it is clear that a failure to restore host immunity leads to worse outcomes. These observations provide clear rationale for the development of novel immunotherapies to...

Abstract Background Corona virus disease has been associated with a wide variety of fungal and bacterial co-infections. These secondary infections could be due to the irrational use antibiotics, immunosuppressive therapy, pre-existing co morbidities, immune modulator effects virus. But here, we report very rare occurring rhino-orbito-cerebral invasive sinusitis in malnourished child no other mo...

BACKGROUND Chronic granulomatous disease (CGD) is an immunodeficiency affecting phagocytic leukocytes. Defective respiratory burst mechanism renders the affected patients to be susceptible to catalase positive microorganisms. With the great successes in antibacterial prophylaxis and therapy, fungal infections are a persistent problem. Invasive aspergillosis is the most important cause of mortal...

This is a case report of chronic maxillary sinusitis caused by root canal overfilling of Calcipex II (Techno-Dent). A 60 year-old male complained of dull pain in the right maxillary molar area after complicated endodontic treatment using Calcipex II paste and was finally diagnosed with a chronic maxillary sinusitis through a clinical and radiological observation. In the biopsy examination, the ...

Most of the information available about Aspergillus infections has originated from the study of A. fumigatus, the most frequent species in the genus. This review aims to compare the pathogenicity and clinical aspects of Aspergillosis caused by A. fumigatus an A. flavus. Experimental data suggests that A. flavus is more virulent than A. fumigatus. However, these were mostly models of disseminate...

Abstract Aims Anecdotal evidence suggests an increase in the incidence of cases Chronic Fungal Sinusitis pre- and post-Covid 19 Pandemic. We aimed to audit our patient fungal sinusitis post-COVID-19 pandemic, alongside auditing management these against national guidelines. Objectives: 1. To assess pandemic at a single UK Tertiary centre 2. patients guidelines post- COVID-19 pandemic. Methods Al...