نتایج جستجو برای: ciliary clearance
تعداد نتایج: 56320 فیلتر نتایج به سال:
Primary ciliary dyskinesia (PCD) is a rare, autosomal recessive disease with abnormalities in the structure of cilia, causing impairment of muco-ciliary clearance with respiratory tract infections, heterotaxia and abnormal sperm motility with male infertility. Here, with a comprehensive literature review, we report a couple with an infertility history of 9 years and three unsuccessful IVF treat...
Mucociliary clearance, vital to lung clearance, is dependent on cilia beat frequency (CBF), coordination of cilia, and the maintenance of periciliary fluid. Adenosine, the metabolic breakdown product of ATP, is an important modulator of ciliary motility. However, the contributions of specific adenosine receptors to key airway ciliary motility processes are unclear. We hypothesized that adenosin...
Airway response of children with primary ciliary dyskinesia to exercise and beta2-agonist challenge.
In primary ciliary dyskinesia (PCD), chest physiotherapy for airway clearance is essential. Exercise and inhaled beta2-agonists can produce bronchodilation thereby augmenting physiotherapy. However, both can also cause bronchoconstriction, and the effects of these stimuli in PCD are not known. In a preliminary study, the mean coefficients of variation for forced expiratory volume in one second ...
BACKGROUND The threat posed by swine influenza viruses with potential to transmit from pig populations to other hosts, including humans, requires the development of new experimental systems to study different aspects of influenza infection. Ex vivo organ culture (EVOC) systems have been successfully used in the study of both human and animal respiratory pathogens. OBJECTIVES We aimed to devel...
Copyright © 2010 Frederick Furness Publishing 20 Chronic sinusitis is one of the most commonly diagnosed chronic illnesses, and approximately 10-15% of the European and US population suffer from chronic rhinosinusitis. Inflammation of the nasal mucosa (i.e. rhinitis), due to bacterial, fungal or viral infections, allergies, or exposure to inhaled irritants, leads to acute sinusitis and CRS. Chr...
purpose: to report a case of ciliary body medulloepithelioma presenting as granulomatous uveitis. patient and finding: a 3-year-old girl presented with chronic granulomatous anterior uveitis in the right eye following unilateral cataract extraction and iol implantation which was unresponsive to topical steroids and intra-vitreal injection of vancomycin and triamcinolone acetonide. one month l...
The airway acts as the first defense against inhaled pathogens and particulate matter from the environment. One major way for the airway to clear inhaled foreign objects is through mucociliary clearance (MCC), an important component of the respiratory innate immune defense against lung disease. MCC is characterized by the upward movement of mucus by ciliary motion that requires a balance betwee...
Recurrent lung infections and pneumonia are emerging as significant comorbidities in the HIV-infected population in the era of combination antiretroviral therapy (cART). HIV infection has been reported to suppress nasal mucociliary clearance (MCC). Since the primary components driving nasal MCC and bronchial MCC are identical, it is possible that bronchial MCC is affected as well. Effective MCC...
BACKGROUND Patients with congenital heart disease (CHD) and heterotaxy show high postsurgical morbidity/mortality, with some developing respiratory complications. Although this finding is often attributed to the CHD, airway clearance and left-right patterning both require motile cilia function. Thus, airway ciliary dysfunction (CD) similar to that of primary ciliary dyskinesia (PCD) may contrib...
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