Introduction. Fecal transplantation was shown to effectively reduce the reoccurrence in patients with refractory Clostridium difficile infection. New data suggest that fecal transplantation could also be efficient in other gastrointestinal diseases, for instance in inflammatory bowel disease, irritable bowel syndrome, but, there are also some data that could imply the efficacy outside the gastr...

Diagnostics and Treatment Sujan C. Reddy, MD; Olivia M. Almendares, MSPH; Wendy Baughman, MSPH; Fernanda C. Lessa, MD; Monica M. Farley, MD; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA; Georgia Emerging Infections Program, Decatur, GA; Atlanta Research and Education Foundation, Decatur, GA; Atlanta VAMedical Center, Decatur, GA; Division of Healthcare Quali...

In this study, we sequenced the complete genome of the Clostridium difficile type strain DSM 1296(T). A combination of single-molecule real-time (SMRT) and Illumina sequencing technology revealed the presence of one chromosome and two extrachromosomal elements, the bacteriophage phiCDIF1296T and a putative plasmid-like structure harboring genes of another bacteriophage.

Clostridium difficile (C. difficile) infection of the small bowel is very rare. The disease course is more severe than that of C. difficile colitis, and the mortality is high. We present a case of C. difficile enteritis in a patient with ileal pouch-anal anastamosis (IPAA), and review previous case reports in order to better characterize this unusual condition.

Species of Clostridium are widely distributed in the environment, inhabiting both human and animal gastrointestinal tracts. Clostridium difficile is an important pathogen associated with outbreaks of pseudomembranous colitis and other intestinal disorders, such as diarrhea. In this study, the prevalence of Clostridium spp. and C. difficile, from hospitalized children with acute diarrhea, was ex...

The antitoxins currently used for the detection of Clostridium difficile by counterimmunoelectrophoresis react with other C. difficile antigens in addition to the toxins produced by the bacterium.

Clostridium difficile-induced diarrhea and colitis are common complications of therapeutic courses of antibiotics in the hospital setting. We report a case of Clostridium difficile colitis following antibiotic prophylaxis for endocarditis prior to dental procedures in the community setting. The infection necessitated hospital admission and a prolonged hospital stay. Dental practitioners must be...

The rates of the predominantly hospital acquired infection, Clostridium difficile, have increased throughout the world. Several risk factors and susceptible patient populations have been identified. Patients with pre-existing liver disease represent an important cohort; recent evidence suggests that Clostridium difficile infection (CDI) is associated with a worse outcome and increased health ca...

This review presents literature data on the prevalence, clinical picture, risk factors of development and modern approaches to diet therapy disease caused by Clostridium difficile (С. difficile). Particular attention is paid methods medical nutrition, taking into account symptoms intoxication organism. Data possibility using domestic products dietary nutrition treatment for restoration function...