intracerebroventricular (icv) injection of streptozotocin (stz) causes cognitive impairment in rats. the beneficial effect of crocus sativus l. extract (cse) was evaluated on icv stz-induced learning, memory, and cognitive impairment in male rats. for this purpose, rats were injected with icv stz bilaterally, on days 1 and 3 (3 mg/kg). the stz-injected rats received cse (60 mg/kg; i.p.) every o...

Although autobiographical memory is an important part of the human mind, there has been little effort on modeling autobiographical memory in autonomous agents. With the motivation of developing human-like intelligence, in this paper, we delineate our approach to enable an agent to maintain memories of its own and to wander in mind. Our model, named Autobiographical Memory-Adaptive Resonance The...

Objective: The study aimed to examine the effect of group reminiscence therapy among elderly people who living nursing homes. 
 Methods: This randomized controlled trial was performed in two homes Turkey. A total 76 recruited intervention (n= 37) and control (n=39). received form sessions lasting 30-45 minutes once a week for six weeks. had no application. Data were collected using socio-d...

Depression is a common disorder in the elderly handicapping patients with affective and cognitive symptoms. Because of their good tolerability relative to the older tricyclic compounds, selective serotonin reuptake inhibitors (SSRIs) are increasingly used for the treatment of depression in the elderly. Little is known about their effects on cognition in elderly patients. In the present 4-wk, si...

[Purpose] In this study, we investigated the effects of combining exercise with a cognitive-enhancement group program on cognition and depression in a group of community-dwelling elderly people. [Subjects and Methods] The study's subjects consisted of 30 community-dwelling elderly people of both genders, whose average age was 78 years. They participated in a program of physical exercise combine...

diabetes mellitus is accompanied with disturbances in learning, memory, and cognitive skills in the humans and experimental animals. due to the anti-diabetic and antioxidant activity of pelargonidin (pg), this research study was conducted to evaluate the efficacy of chronic oral pg on alleviating learning and memory disturbance in streptozotocin-diabetic rats. male wistar rats were divided into...

While considerable knowledge has been gained through the use of established cognitive and motor assessment tools, there is a considerable interest and need for the development of a battery of reliable and validated assessment tools that provide real-time and remote analysis of cognitive and motor function in the elderly. Smartphones appear to be an obvious choice for the development of these "n...

CONTEXT The role of macrostructural white matter changes, such as atrophy and white matter lesions, in cognitive decline is increasingly being recognized. However, in the elderly population, these macrostructural changes do not account for all variability in cognition. Measures reflecting white matter microstructural integrity may provide additional information to investigate the relation betwe...