Background: The extent to which homeostatically regulated physiological processes (including cardiorespiratory fitness expressed as VO2max) are involved in response physical stressors (which include acclimatization and marching) has not been studied,, we intended make this assessment based on measured cortisol levels blood lactate subjects exposed summer winter marching.
 Methods: Two grou...

BACKGROUND The physiological challenges posed by hypobaric hypoxia warrant exploration of pharmacological entities to improve acclimatization to hypoxia. The present study investigates the preclinical efficacy of sphingosine-1-phosphate (S1P) to improve acclimatization to simulated hypobaric hypoxia. EXPERIMENTAL APPROACH Efficacy of intravenously administered S1P in improving haematological ...

strawberry is a valuable, nutritious, and economically important fruit all over the world including bangladesh. therefore, there is a demand to develop a suitable variety of strawberry. for this purpose, leaf explants from in vitro grown strawberry plantlets were cultured onto ms medium supplemented with different concentrations and combinations of 2,4-d, naa and ba for callus induction. the mo...

chilling is an important environmental stress that influences the yield and quality of many agricultural crops. different plants use different systems to endure this stress and minimize its effects. one of these systems is enzymatic reaction. to find out more about responses of different grapevine species and cultivars to the low temperature conditions, their enzymatic changes were evaluated in...

BACKGROUND Chilblains are quite often seen in various parts, in particular cold weather areas of Pakistan. Unfortunately, no studies have so far been carried out in Pakistan, to determine epidemiological aspects of chilblains. The objective of this study was to see the epidemiological patterns of chilblains at a moderately cold weather station. METHODS The study was conducted at Dermatology o...

We used experimental evolution to test directly the important and commonplace evolutionary hypothesis that adaptation, increased fitness within the selective environment, is accompanied by trade-off, a loss of fitness in other nonselective environments. Specifically, we determined whether trade-offs at high temperature generally and necessarily accompany genetic adaptation to low temperature. W...

Low temperature tolerance is the main predictor of variation in the global distribution and performance of insects, yet the molecular mechanisms underlying cold tolerance variation are poorly known, and it is unclear whether the mechanisms that improve cold tolerance within the lifetime of an individual insect are similar to those that underlie evolved differences among species. The accumulatio...

Several lines of evidence such as the basal location of thermophilic lineages in large-scale phylogenetic trees and the ancestral sequence reconstruction of single enzymes or large protein concatenations support the conclusion that the ancestors of the bacterial and archaeal domains were thermophilic organisms which were adapted to hot environments during the early stages of the Earth. A parsim...